Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 173202..173382 Replicon chromosome
Accession NZ_CP035791
Organism Staphylococcus aureus strain 592

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag ERW13_RS01130 Protein ID WP_001801861.1
Coordinates 173287..173382 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 173202..173259 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ERW13_RS01100 168911..169045 + 135 WP_001791797.1 hypothetical protein -
ERW13_RS01105 169209..170765 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
ERW13_RS01110 170758..171987 + 1230 WP_000072627.1 restriction endonuclease subunit S -
ERW13_RS01115 172439..172933 + 495 Protein_175 transposase -
ERW13_RS01120 172924..173085 + 162 Protein_176 transposase -
ERW13_RS01125 173063..173164 - 102 WP_001792025.1 hypothetical protein -
- 173202..173259 + 58 - - Antitoxin
ERW13_RS01130 173287..173382 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
ERW13_RS01135 173527..174539 + 1013 Protein_179 IS3 family transposase -
ERW13_RS01140 174737..175309 - 573 WP_000414216.1 hypothetical protein -
ERW13_RS01145 175410..175751 - 342 WP_000627540.1 DUF3969 family protein -
ERW13_RS01150 175792..176418 - 627 WP_000669024.1 hypothetical protein -
ERW13_RS01155 176493..177488 - 996 WP_000070642.1 DUF4352 domain-containing protein -
ERW13_RS01160 177569..178219 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 146369..178977 32608


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T118514 WP_001801861.1 NZ_CP035791:c173382-173287 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T118514 NZ_CP035791:c173382-173287 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT118514 NZ_CP035791:173202-173259 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References