Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1908824..1909004 Replicon chromosome
Accession NZ_CP018768
Organism Staphylococcus aureus strain UCI 28 isolate ST5

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag BSG37_RS15115 Protein ID WP_001801861.1
Coordinates 1908824..1908919 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1908947..1909004 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSG37_RS09540 1903987..1904637 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
BSG37_RS09545 1904718..1905713 + 996 WP_000070642.1 DUF4352 domain-containing protein -
BSG37_RS09550 1905788..1906414 + 627 WP_000669024.1 hypothetical protein -
BSG37_RS09555 1906455..1906796 + 342 WP_000627540.1 DUF3969 family protein -
BSG37_RS09560 1906897..1907469 + 573 WP_000414216.1 hypothetical protein -
BSG37_RS14985 1907667..1908679 - 1013 Protein_1800 IS3 family transposase -
BSG37_RS15115 1908824..1908919 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1908947..1909004 - 58 - - Antitoxin
BSG37_RS09575 1909042..1909143 + 102 WP_001792025.1 hypothetical protein -
BSG37_RS15120 1909121..1909282 - 162 Protein_1803 transposase -
BSG37_RS09585 1909273..1909767 - 495 Protein_1804 transposase -
BSG37_RS09590 1910219..1911448 - 1230 WP_000072627.1 restriction endonuclease subunit S -
BSG37_RS09595 1911441..1912997 - 1557 WP_000028669.1 type I restriction-modification system subunit M -
BSG37_RS09600 1913161..1913295 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1903228..1935837 32609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T70430 WP_001801861.1 NZ_CP018768:1908824-1908919 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T70430 NZ_CP018768:1908824-1908919 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT70430 NZ_CP018768:c1909004-1908947 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References