Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 410415..410595 Replicon chromosome
Accession NZ_CP029086
Organism Staphylococcus aureus strain AR462

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSC48_RS02070 Protein ID WP_001801861.1
Coordinates 410415..410510 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 410538..410595 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSC48_RS02040 405578..406228 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
CSC48_RS02045 406309..407304 + 996 WP_000070642.1 DUF4352 domain-containing protein -
CSC48_RS02050 407379..408005 + 627 WP_000669024.1 hypothetical protein -
CSC48_RS02055 408046..408387 + 342 WP_000627540.1 DUF3969 family protein -
CSC48_RS02060 408488..409060 + 573 WP_000414216.1 hypothetical protein -
CSC48_RS02065 409258..410270 - 1013 Protein_366 IS3 family transposase -
CSC48_RS02070 410415..410510 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 410538..410595 - 58 - - Antitoxin
CSC48_RS02075 410633..410734 + 102 WP_001792025.1 hypothetical protein -
CSC48_RS02080 410712..410873 - 162 Protein_369 transposase -
CSC48_RS02085 410864..411358 - 495 Protein_370 transposase -
CSC48_RS02090 411810..413039 - 1230 WP_000072627.1 restriction endonuclease subunit S -
CSC48_RS02095 413032..414588 - 1557 WP_031862851.1 type I restriction-modification system subunit M -
CSC48_RS02100 414752..414886 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 404820..436551 31731


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T104785 WP_001801861.1 NZ_CP029086:410415-410510 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T104785 NZ_CP029086:410415-410510 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT104785 NZ_CP029086:c410595-410538 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References