114836

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1891179..1891359 Replicon chromosome
Accession NZ_CP033996
Organism Staphylococcus aureus strain P1D9C1

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag EFD73_RS09105 Protein ID WP_001801861.1
Coordinates 1891179..1891274 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1891302..1891359 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EFD73_RS09075 1886342..1886992 + 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -
EFD73_RS09080 1887073..1888068 + 996 WP_000070642.1 DUF4352 domain-containing protein -
EFD73_RS09085 1888143..1888769 + 627 WP_000669024.1 hypothetical protein -
EFD73_RS09090 1888810..1889151 + 342 WP_000627540.1 DUF3969 family protein -
EFD73_RS09095 1889252..1889824 + 573 WP_000414216.1 hypothetical protein -
EFD73_RS09100 1890022..1891034 - 1013 Protein_1774 IS3 family transposase -
EFD73_RS09105 1891179..1891274 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1891302..1891359 - 58 - - Antitoxin
EFD73_RS09110 1891397..1891498 + 102 WP_001792025.1 hypothetical protein -
EFD73_RS09115 1891476..1891637 - 162 Protein_1777 transposase -
EFD73_RS09120 1891628..1892122 - 495 Protein_1778 transposase -
EFD73_RS09125 1892574..1893803 - 1230 WP_000072627.1 restriction endonuclease subunit S -
EFD73_RS09130 1893796..1895352 - 1557 WP_064135920.1 type I restriction-modification system subunit M -
EFD73_RS09135 1895516..1895650 - 135 WP_001791797.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - lukD / hlgA / selk 1885584..1919985 34401


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(30-58)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T114836 WP_001801861.1 NZ_CP033996:1891179-1891274 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T114836 NZ_CP033996:1891179-1891274 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT114836 NZ_CP033996:c1891359-1891302 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References