Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 174676..174856 Replicon chromosome
Accession NZ_CP062388
Organism Staphylococcus aureus strain NAS_AN_044

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag IF700_RS01095 Protein ID WP_001801861.1
Coordinates 174761..174856 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 174676..174733 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IF700_RS01065 170385..170519 + 135 WP_001791797.1 hypothetical protein -
IF700_RS01070 170683..172239 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
IF700_RS01075 172232..173461 + 1230 WP_000072627.1 restriction endonuclease subunit S -
IF700_RS01080 174003..174413 + 411 WP_001808705.1 IS21 family transposase -
IF700_RS01085 174398..174559 + 162 Protein_178 transposase -
IF700_RS01090 174537..174638 - 102 WP_001792025.1 hypothetical protein -
- 174676..174733 + 58 - - Antitoxin
IF700_RS01095 174761..174856 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
IF700_RS01100 175001..176013 + 1013 Protein_181 IS3 family transposase -
IF700_RS01105 176211..176783 - 573 WP_000414216.1 hypothetical protein -
IF700_RS01110 176884..177225 - 342 WP_000627540.1 DUF3969 family protein -
IF700_RS01115 177266..177892 - 627 WP_000669024.1 hypothetical protein -
IF700_RS01120 177967..178962 - 996 WP_000070642.1 DUF4352 domain-containing protein -
IF700_RS01125 179043..179693 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 147843..179657 31814


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T174789 WP_001801861.1 NZ_CP062388:c174856-174761 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T174789 NZ_CP081677:3701374-3701592 [Escherichia coli]
ATGTCCGAAAAACCTTTAACGAAAACCGATTATTTAATGCGTTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGTGT
TATCGAGAAAAATAAATACGAATTATCAGATAATGAACTGGCGGTATTTTACTCAGCCGCAGATCACCGCCTCGCCGAAT
TGACCATGAATAAACTGTACGACAAGATCCCTTCCTCAGTTTGGAAATTTATTCGCTAA

Antitoxin


Download         Length: 58 bp

>AT174789 NZ_CP062388:174676-174733 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References