Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 559936..560116 Replicon chromosome
Accession NZ_CP029680
Organism Staphylococcus aureus strain AR_0215

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag CSB71_RS03480 Protein ID WP_001801861.1
Coordinates 560021..560116 (-) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 559936..559993 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CSB71_RS03450 555645..555779 + 135 WP_001791797.1 hypothetical protein -
CSB71_RS03455 555943..557499 + 1557 WP_000028669.1 type I restriction-modification system subunit M -
CSB71_RS03460 557492..558721 + 1230 WP_000072627.1 restriction endonuclease subunit S -
CSB71_RS03465 559173..559667 + 495 Protein_577 transposase -
CSB71_RS03470 559658..559819 + 162 Protein_578 transposase -
CSB71_RS03475 559797..559898 - 102 WP_001792025.1 hypothetical protein -
- 559936..559993 + 58 - - Antitoxin
CSB71_RS03480 560021..560116 - 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
CSB71_RS03485 560261..561273 + 1013 Protein_581 IS3 family transposase -
CSB71_RS03490 561471..562043 - 573 WP_000414216.1 hypothetical protein -
CSB71_RS03495 562144..562485 - 342 WP_000627540.1 DUF3969 family protein -
CSB71_RS03500 562526..563152 - 627 WP_000669024.1 hypothetical protein -
CSB71_RS03505 563227..564222 - 996 WP_110179682.1 DUF4352 domain-containing protein -
CSB71_RS03510 564303..564953 - 651 WP_001795210.1 excalibur calcium-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Prophage - selk / hlgA / lukD 533103..565712 32609


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T106314 WP_001801861.1 NZ_CP029680:c560116-560021 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T106314 NZ_CP029680:c560116-560021 [Staphylococcus aureus]
GTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAG
ACGCAATACAAAATAG

Antitoxin


Download         Length: 58 bp

>AT106314 NZ_CP029680:559936-559993 [Staphylococcus aureus]
AACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References