Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2828320..2828876 Replicon chromosome
Accession NC_003919
Organism Xanthomonas axonopodis pv. citri str. 306

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag XAC_RS12345 Protein ID WP_011051576.1
Coordinates 2828320..2828610 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag XAC_RS12350 Protein ID WP_004541313.1
Coordinates 2828598..2828876 (-) Length 93 a.a.

Genomic Context

XAC_RS12365XAC_RS12370XAC_RS25605XAC_RS26110XAC_RS12320XAC_RS12325XAC_RS12335XAC_RS12340XAC_RS12345XAC_RS12350XAC_RS12355
Location: 2830363..2831588 (1226 bp)
Type: Others
Protein ID: Protein_2421
Location: 2832206..2833162 (957 bp)
Type: Others
Protein ID: WP_197707729.1
Location: 2823631..2823771 (141 bp)
Type: Others
Protein ID: WP_157860651.1
Location: 2824057..2825013 (957 bp)
Type: Others
Protein ID: WP_011051571.1
Location: 2825080..2826213 (1134 bp)
Type: Others
Protein ID: Protein_2414
Location: 2826253..2827340 (1088 bp)
Type: Others
Protein ID: Protein_2415
Location: 2827553..2827732 (180 bp)
Type: Others
Protein ID: WP_015463309.1
Location: 2828003..2828317 (315 bp)
Type: Others
Protein ID: WP_015463310.1
Location: 2828320..2828610 (291 bp)
Type: Toxin
Protein ID: WP_011051576.1
Location: 2828598..2828876 (279 bp)
Type: Antitoxin
Protein ID: WP_004541313.1
Location: 2829046..2830314 (1269 bp)
Type: Others
Protein ID: Protein_2420
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
XAC_RS256052823631..2823771-141WP_157860651.1hypothetical protein-
XAC_RS26110 (XAC2422)2824057..2825013-957WP_011051571.1hypothetical protein-
XAC_RS12320 (XAC2423)2825080..2826213-1134Protein_2414IS5 family transposase-
XAC_RS12325 (XAC2424)2826253..2827340-1088Protein_2415IS3 family transposase-
XAC_RS123352827553..2827732-180WP_015463309.1hypothetical protein-
XAC_RS123402828003..2828317-315WP_015463310.1hypothetical protein-
XAC_RS12345 (XAC2428)2828320..2828610-291WP_011051576.1type II toxin-antitoxin system RelE/ParE family toxinToxin
XAC_RS12350 (XAC2429)2828598..2828876-279WP_004541313.1CopG family ribbon-helix-helix proteinAntitoxin
XAC_RS12355 (XAC2430)2829046..2830314-1269Protein_2420transposase-
XAC_RS12365 (XAC2432)2830363..2831588+1226Protein_2421IS3 family transposase-
XAC_RS12370 (XAC2433)2832206..2833162+957WP_197707729.1recombinase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideGenomic island--2820490..284701026520
insideIScluster/Tn--2825080..28315886508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T20720 WP_011051576.1 NC_003919:c2828610-2828320 [Xanthomonas citri pv. citri str. 306]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T20720 NC_003919:c2828610-2828320 [Xanthomonas citri pv. citri str. 306]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT20720 WP_004541313.1 NC_003919:c2828876-2828598 [Xanthomonas citri pv. citri str. 306]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT20720 NC_003919:c2828876-2828598 [Xanthomonas citri pv. citri str. 306]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBM4UBZ0

References