Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 673542..674098 Replicon chromosome
Accession NZ_CP018850
Organism Xanthomonas citri pv. citri strain LJ207-7

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BI315_RS03045 Protein ID WP_011051576.1
Coordinates 673542..673832 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag BI315_RS03050 Protein ID WP_004541313.1
Coordinates 673820..674098 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI315_RS03015 669342..669710 + 369 WP_015472110.1 hypothetical protein -
BI315_RS25280 669817..670010 - 194 Protein_554 hypothetical protein -
BI315_RS03020 670302..671435 - 1134 Protein_555 IS5 family transposase -
BI315_RS03025 671475..672562 - 1088 Protein_556 IS3 family transposase -
BI315_RS03035 672775..672954 - 180 WP_015463309.1 hypothetical protein -
BI315_RS03040 673225..673545 - 321 WP_099522003.1 hypothetical protein -
BI315_RS03045 673542..673832 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BI315_RS03050 673820..674098 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
BI315_RS03055 674268..675536 - 1269 Protein_561 transposase -
BI315_RS03065 675585..676810 + 1226 Protein_562 IS3 family transposase -
BI315_RS03070 677445..678383 + 939 WP_043930788.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 665712..692231 26519
inside IScluster/Tn - - 670302..676810 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T70704 WP_011051576.1 NZ_CP018850:c673832-673542 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T70704 NZ_CP018850:c673832-673542 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT70704 WP_004541313.1 NZ_CP018850:c674098-673820 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT70704 NZ_CP018850:c674098-673820 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References