170426

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2889493..2890049 Replicon chromosome
Accession NZ_CP060453
Organism Xanthomonas citri pv. citri strain DAR73909

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H8Z74_RS12630 Protein ID WP_011051576.1
Coordinates 2889493..2889783 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag H8Z74_RS12635 Protein ID WP_004541313.1
Coordinates 2889771..2890049 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8Z74_RS12605 2885230..2886186 - 957 WP_011051571.1 hypothetical protein -
H8Z74_RS12610 2886253..2887386 - 1134 Protein_2458 IS5 family transposase -
H8Z74_RS12615 2887426..2888513 - 1088 Protein_2459 IS3 family transposase -
H8Z74_RS12620 2888726..2888905 - 180 WP_015463309.1 hypothetical protein -
H8Z74_RS12625 2889176..2889490 - 315 WP_015463310.1 hypothetical protein -
H8Z74_RS12630 2889493..2889783 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H8Z74_RS12635 2889771..2890049 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
H8Z74_RS12640 2890219..2891487 - 1269 Protein_2464 transposase -
H8Z74_RS12645 2891536..2892761 + 1226 Protein_2465 IS3 family transposase -
H8Z74_RS12650 2893380..2894336 + 957 WP_197707729.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside IScluster/Tn - - 2886253..2892761 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T170426 WP_011051576.1 NZ_CP060453:c2889783-2889493 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T170426 NZ_CP077366:c2705014-2704832 [Pantoea agglomerans]
ATGAAGTACAGTGAATTCAGACGCTGGCTCATTCAGCAGGGCGCTATTTTGACTAAGCACCGCAGTGGAAGCAGCCATTT
CAAGGTCTTCCTGGGCGACAGGCAATCCATTTTTCCGGATCACGGAGCAAAAGAAATGCCTGAAGGTACGCGCAGAAAAA
TTTTAAAAGATCTGGGCCTGTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT170426 WP_004541313.1 NZ_CP060453:c2890049-2889771 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT170426 NZ_CP077366:c2704810-2704385 [Pantoea agglomerans]
ATGTTTAATTATGCCGTCAGATTAACTCATGACGCCAAAACCGATACCTATGAGGTCTCGTGTCGTGATTTGCCGTTACT
GCATTCCGTCGGTGACACCGTTGAGGAAGCACTTGCAGAAGCCGAAGATGGACTGGTGACGGCAATCTCTCTCGAGATGG
ATACGCGTCGTCCGATTCCGGTTGCCAGTAAACCGCTGGAAGGAGAGTACATTGTCTCTGTGCCTGTACTGGTGGCAATG
AAAGCGGCACTTTACAACGCAATGATTGAAACCGGCACCCGTAAAGTCGATCTGGCACGTCAGCTGGGCGTGAATGGCCC
ACAGGTTGATCGACTACTGGATGTAGAGCACTCATCGAAAGTCGAAAATGTGGAGCTGGCGCTGGCTCAGCTGGGACGCA
AAGCCCGGATTGAAATTCGTACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References