70719

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 802433..802989 Replicon chromosome
Accession NZ_CP018858
Organism Xanthomonas citri pv. citri strain LH201

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BJD09_RS03555 Protein ID WP_011051576.1
Coordinates 802699..802989 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag BJD09_RS03550 Protein ID WP_004541313.1
Coordinates 802433..802711 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BJD09_RS03530 798147..799085 - 939 WP_043930788.1 recombinase family protein -
BJD09_RS03535 799721..800946 - 1226 Protein_659 IS3 family transposase -
BJD09_RS03545 800995..802263 + 1269 Protein_660 transposase -
BJD09_RS03550 802433..802711 + 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
BJD09_RS03555 802699..802989 + 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BJD09_RS03560 802986..803306 + 321 WP_099522003.1 hypothetical protein -
BJD09_RS03565 803577..803756 + 180 WP_015463309.1 hypothetical protein -
BJD09_RS03575 803968..805055 + 1088 Protein_665 IS3 family transposase -
BJD09_RS03580 805095..806228 + 1134 Protein_666 IS5 family transposase -
BJD09_RS25045 806520..806713 + 194 Protein_667 hypothetical protein -
BJD09_RS03585 806820..807188 - 369 WP_015472110.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 784895..812810 27915
inside IScluster/Tn - - 799721..806228 6507


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T70719 WP_011051576.1 NZ_CP018858:802699-802989 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T70719 NZ_CP018858:802699-802989 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT70719 WP_004541313.1 NZ_CP018858:802433-802711 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT70719 NZ_CP018858:802433-802711 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References