Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2308501..2309057 Replicon chromosome
Accession NZ_CP009031
Organism Xanthomonas citri pv. citri strain AW13

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AMD09_RS10445 Protein ID WP_011051576.1
Coordinates 2308501..2308791 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag AMD09_RS10450 Protein ID WP_004541313.1
Coordinates 2308779..2309057 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD09_RS26180 2304238..2305194 - 957 WP_011051571.1 hypothetical protein -
AMD09_RS10420 2305261..2306394 - 1134 Protein_1972 IS5 family transposase -
AMD09_RS10425 2306434..2307521 - 1088 Protein_1973 IS3 family transposase -
AMD09_RS10435 2307734..2307913 - 180 WP_015463309.1 hypothetical protein -
AMD09_RS10440 2308184..2308498 - 315 WP_015463310.1 hypothetical protein -
AMD09_RS10445 2308501..2308791 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AMD09_RS10450 2308779..2309057 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
AMD09_RS10455 2309227..2310495 - 1269 Protein_1978 transposase -
AMD09_RS10465 2310544..2311769 + 1226 Protein_1979 IS3 family transposase -
AMD09_RS10470 2312388..2313344 + 957 WP_015472114.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2300671..2327200 26529
inside IScluster/Tn - - 2305261..2311769 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T48121 WP_011051576.1 NZ_CP009031:c2308791-2308501 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T48121 NZ_CP009031:c2308791-2308501 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT48121 WP_004541313.1 NZ_CP009031:c2309057-2308779 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT48121 NZ_CP009031:c2309057-2308779 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGCGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References