48106

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2828312..2828868 Replicon chromosome
Accession NZ_CP009025
Organism Xanthomonas citri pv. citri strain BL18

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AMD12_RS12800 Protein ID WP_011051576.1
Coordinates 2828312..2828602 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag AMD12_RS12805 Protein ID WP_004541313.1
Coordinates 2828590..2828868 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD12_RS25250 2824049..2825005 - 957 WP_011051571.1 hypothetical protein -
AMD12_RS12775 2825072..2826205 - 1134 Protein_2412 IS5 family transposase -
AMD12_RS12780 2826245..2827332 - 1088 Protein_2413 IS3 family transposase -
AMD12_RS12790 2827545..2827724 - 180 WP_015463309.1 hypothetical protein -
AMD12_RS12795 2827995..2828309 - 315 WP_015463310.1 hypothetical protein -
AMD12_RS12800 2828312..2828602 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AMD12_RS12805 2828590..2828868 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
AMD12_RS12810 2829038..2830306 - 1269 Protein_2418 transposase -
AMD12_RS12820 2830355..2831580 + 1226 Protein_2419 IS3 family transposase -
AMD12_RS12825 2832198..2833154 + 957 WP_197707729.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2820482..2847002 26520
inside IScluster/Tn - - 2825072..2831580 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T48106 WP_011051576.1 NZ_CP009025:c2828602-2828312 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T48106 NZ_CP009025:c2828602-2828312 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT48106 WP_004541313.1 NZ_CP009025:c2828868-2828590 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT48106 NZ_CP009025:c2828868-2828590 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References