Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2308685..2309241 Replicon chromosome
Accession NC_020815
Organism Xanthomonas citri subsp. citri Aw12879

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag XCAW_RS10075 Protein ID WP_011051576.1
Coordinates 2308685..2308975 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag XCAW_RS10080 Protein ID WP_004541313.1
Coordinates 2308963..2309241 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XCAW_RS26615 2304422..2305378 - 957 WP_011051571.1 hypothetical protein -
XCAW_RS10050 2305445..2306578 - 1134 Protein_1974 IS5 family transposase -
XCAW_RS10055 2306618..2307705 - 1088 Protein_1975 IS3 family transposase -
XCAW_RS10065 2307918..2308097 - 180 WP_015463309.1 hypothetical protein -
XCAW_RS10070 2308368..2308682 - 315 WP_015463310.1 hypothetical protein -
XCAW_RS10075 2308685..2308975 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
XCAW_RS10080 2308963..2309241 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
XCAW_RS10085 2309411..2310679 - 1269 Protein_1980 transposase -
XCAW_RS10095 2310728..2311953 + 1226 Protein_1981 IS3 family transposase -
XCAW_RS10100 2312572..2313528 + 957 WP_015472114.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2300855..2327384 26529
inside IScluster/Tn - - 2305445..2311953 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T29262 WP_011051576.1 NC_020815:c2308975-2308685 [Xanthomonas citri subsp. citri Aw12879]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T29262 NC_020815:c2308975-2308685 [Xanthomonas citri subsp. citri Aw12879]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT29262 WP_004541313.1 NC_020815:c2309241-2308963 [Xanthomonas citri subsp. citri Aw12879]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT29262 NC_020815:c2309241-2308963 [Xanthomonas citri subsp. citri Aw12879]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGCGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References