Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2889391..2889947 Replicon chromosome
Accession NZ_CP060446
Organism Xanthomonas citri pv. citri strain DAR72029

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H8Z73_RS12620 Protein ID WP_011051576.1
Coordinates 2889391..2889681 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag H8Z73_RS12625 Protein ID WP_004541313.1
Coordinates 2889669..2889947 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8Z73_RS12595 2885128..2886084 - 957 WP_011051571.1 hypothetical protein -
H8Z73_RS12600 2886151..2887284 - 1134 Protein_2456 IS5 family transposase -
H8Z73_RS12605 2887324..2888411 - 1088 Protein_2457 IS3 family transposase -
H8Z73_RS12610 2888624..2888803 - 180 WP_015463309.1 hypothetical protein -
H8Z73_RS12615 2889074..2889388 - 315 WP_015463310.1 hypothetical protein -
H8Z73_RS12620 2889391..2889681 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H8Z73_RS12625 2889669..2889947 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
H8Z73_RS12630 2890117..2891385 - 1269 Protein_2462 transposase -
H8Z73_RS12635 2891434..2892659 + 1226 Protein_2463 IS3 family transposase -
H8Z73_RS12640 2893278..2894234 + 957 WP_197707729.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2878491..2910645 32154
inside IScluster/Tn - - 2886151..2892659 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T170418 WP_011051576.1 NZ_CP060446:c2889681-2889391 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T170418 NZ_CP077338:167585-167881 [Acinetobacter lwoffii]
ATGATTGAAATTAAACGTCTGCCAGAATTTGATGAATGGTTGGATGGCATTAAAGACAATATGACCCGTATCCGCCTGAA
TCGTCGATTAGATAAGGTTCAACGTGGAAACTGGGGAGACATTAAACCTCTCCAAGATGGCGTTTGGGAAATGAGAGAAT
TCTTCGGTTCTGGATGGAGGATGTATTACATCCAACATGGTGACGTTGTGATTGTAATGCTTGGTGGTGGAGATAAATCA
ACTCAACAACAAGACATCGATCGTGCAGTCAAACTATCGAAAACGTTGGAGGATTAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT170418 WP_004541313.1 NZ_CP060446:c2889947-2889669 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT170418 NZ_CP077338:167883-168173 [Acinetobacter lwoffii]
ATGGTTAAAGTAGCTGATTTACCAAGTTTTGATATGGCTGAGTCACTCAAAACTGAAGAAGACATTGTGATTTATCTCAA
TATGGTTCTTGAAGAGAATGATCCAGCTGAATTAGCTCATGCACTTGGTGTTATTGCTAAAGCTCGTGGCATGACTCAAA
TCGCTAAAGAAGCAGGGATTGGGCGTGAGGCACTCTACAAAGCCCTACGTCATGATTCAGCACCACGTTTTGATACAATT
AATCGTGTAGTAAATGCTTTAGGCTTAAAACTCACAGTACAACACGCCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References