Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2817150..2817706 Replicon chromosome
Accession NZ_CP011827
Organism Xanthomonas citri pv. citri strain jx-6

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AB890_RS12355 Protein ID WP_011051576.1
Coordinates 2817150..2817440 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag AB890_RS12360 Protein ID WP_004541313.1
Coordinates 2817428..2817706 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AB890_RS12325 2812950..2813318 + 369 WP_015472110.1 hypothetical protein -
AB890_RS23310 2813425..2813618 - 194 Protein_2399 hypothetical protein -
AB890_RS12330 2813910..2815043 - 1134 Protein_2400 IS5 family transposase -
AB890_RS12335 2815083..2816170 - 1088 Protein_2401 IS3 family transposase -
AB890_RS12345 2816383..2816562 - 180 WP_015463309.1 hypothetical protein -
AB890_RS12350 2816833..2817153 - 321 WP_099522003.1 hypothetical protein -
AB890_RS12355 2817150..2817440 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AB890_RS12360 2817428..2817706 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
AB890_RS12365 2817876..2819144 - 1269 Protein_2406 transposase -
AB890_RS12375 2819193..2820418 + 1226 Protein_2407 IS3 family transposase -
AB890_RS12380 2821055..2821993 + 939 WP_044022138.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2809320..2835841 26521
inside IScluster/Tn - - 2813910..2820418 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T55074 WP_011051576.1 NZ_CP011827:c2817440-2817150 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T55074 NZ_CP011827:c2817440-2817150 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT55074 WP_004541313.1 NZ_CP011827:c2817706-2817428 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT55074 NZ_CP011827:c2817706-2817428 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References