Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 3019322..3019878 Replicon chromosome
Accession NZ_CP066343
Organism Xanthomonas citri pv. durantae strain LMG696

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag Xdur_RS13410 Protein ID WP_230598886.1
Coordinates 3019322..3019573 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag Xdur_RS13415 Protein ID WP_004541313.1
Coordinates 3019600..3019878 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Xdur_RS13380 (Xdur_013350) 3015059..3016015 - 957 WP_011051571.1 hypothetical protein -
Xdur_RS13385 (Xdur_013355) 3016082..3017215 - 1134 Protein_2616 IS5 family transposase -
Xdur_RS13395 (Xdur_013365) 3018555..3018809 - 255 WP_223293127.1 hypothetical protein -
Xdur_RS13400 3018878..3019012 - 135 WP_011051575.1 hypothetical protein -
Xdur_RS13405 (Xdur_013370) 3019005..3019319 - 315 WP_015463310.1 hypothetical protein -
Xdur_RS13410 (Xdur_013375) 3019322..3019573 - 252 WP_230598886.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
Xdur_RS13415 (Xdur_013380) 3019600..3019878 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
Xdur_RS13420 (Xdur_013385) 3020048..3021316 - 1269 Protein_2623 Tn3 family transposase -
Xdur_RS13425 (Xdur_013390) 3021365..3022590 + 1226 Protein_2624 IS3 family transposase -
Xdur_RS13430 (Xdur_013395) 3023227..3023934 + 708 Protein_2625 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 3009508..3039521 30013
inside IScluster/Tn - - 3016082..3022590 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9519.85 Da        Isoelectric Point: 10.2314

>T184303 WP_230598886.1 NZ_CP066343:c3019573-3019322 [Xanthomonas citri pv. durantae]
MQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T184303 NZ_CP087608:155055-155471 [Klebsiella pneumoniae subsp. pneumoniae]
GTGAACAAGACCTATATGCTCGACACCTGTATCTGCTCGTTCATCATGCGCGAGCAGCCGGAAGCCGTCCTGAAGCGCCT
GGAGCAGGCGGTGCTGCGCGGCCAGCGCATCGTTGTCTCGGCCATCACTTATTCTGAAATGCGCTTCGGGGCCACCGGCC
CGAAGGCCTCCCCGCGCCACGTCGAGCTGGTCGACGCGTTCTGCGCCCGCCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGACGCCACCACGGAGATTAAGGTGGCGCTGCGAATGGCCGGGACGCCGATCGGCCCGAACGACACGGCCATTGC
CGGGCACGCCATCGCCGCCGGTGCCGTGCTGGTGACGAATAATACGCGGGAATTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT184303 WP_004541313.1 NZ_CP066343:c3019878-3019600 [Xanthomonas citri pv. durantae]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT184303 NZ_CP087608:154828-155058 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAGAACTGTATCCATTTTTAAAAACGGCAATAACCGCGCCATTCGTCTGCCCCGCGATCTGGATTTTGAGGGAGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATTATTTTGCGTCCCGTCCGGCCGACCTGGGGCTCGTTCGCGCAGTTCG
AGAAGGCAGACCCGGACTTTATGGCGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References