Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2817204..2817760 Replicon chromosome
Accession NZ_CP023662
Organism Xanthomonas citri pv. citri strain Xcc49

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CPA10_RS12920 Protein ID WP_011051576.1
Coordinates 2817204..2817494 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CPA10_RS12925 Protein ID WP_040259533.1
Coordinates 2817482..2817760 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CPA10_RS23995 2812941..2813897 - 957 WP_011051571.1 hypothetical protein -
CPA10_RS12900 2813964..2815097 - 1134 Protein_2391 IS5 family transposase -
CPA10_RS12905 2815137..2816224 - 1088 Protein_2392 IS3 family transposase -
CPA10_RS12910 2816437..2816616 - 180 WP_015463309.1 hypothetical protein -
CPA10_RS12915 2816887..2817201 - 315 WP_015463310.1 hypothetical protein -
CPA10_RS12920 2817204..2817494 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CPA10_RS12925 2817482..2817760 - 279 WP_040259533.1 CopG family ribbon-helix-helix protein Antitoxin
CPA10_RS12930 2817930..2819198 - 1269 Protein_2397 transposase -
CPA10_RS12935 2819247..2820472 + 1226 Protein_2398 IS3 family transposase -
CPA10_RS12940 2821091..2822047 + 957 WP_015463313.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2809374..2835894 26520
inside IScluster/Tn - - 2813964..2820472 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T85842 WP_011051576.1 NZ_CP023662:c2817494-2817204 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T85842 NZ_CP023662:c2817494-2817204 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10829.16 Da        Isoelectric Point: 4.9801

>AT85842 WP_040259533.1 NZ_CP023662:c2817760-2817482 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLRVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT85842 NZ_CP023662:c2817760-2817482 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCGCGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References