Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2308453..2309009 Replicon chromosome
Accession NZ_CP009040
Organism Xanthomonas citri pv. citri strain AW16

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AMD06_RS10445 Protein ID WP_011051576.1
Coordinates 2308453..2308743 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag AMD06_RS10450 Protein ID WP_004541313.1
Coordinates 2308731..2309009 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD06_RS26065 2304190..2305146 - 957 WP_011051571.1 hypothetical protein -
AMD06_RS10420 2305213..2306346 - 1134 Protein_1971 IS5 family transposase -
AMD06_RS10425 2306386..2307473 - 1088 Protein_1972 IS3 family transposase -
AMD06_RS10435 2307686..2307865 - 180 WP_015463309.1 hypothetical protein -
AMD06_RS10440 2308136..2308450 - 315 WP_015463310.1 hypothetical protein -
AMD06_RS10445 2308453..2308743 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AMD06_RS10450 2308731..2309009 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
AMD06_RS10455 2309179..2310447 - 1269 Protein_1977 transposase -
AMD06_RS10465 2310496..2311721 + 1226 Protein_1978 IS3 family transposase -
AMD06_RS10470 2312340..2313296 + 957 WP_015472114.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2300623..2327152 26529
inside IScluster/Tn - - 2305213..2311721 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T48142 WP_011051576.1 NZ_CP009040:c2308743-2308453 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T48142 NZ_CP009040:c2308743-2308453 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT48142 WP_004541313.1 NZ_CP009040:c2309009-2308731 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT48142 NZ_CP009040:c2309009-2308731 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGCGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References