Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2816065..2816621 Replicon chromosome
Accession NZ_CP059999
Organism Xanthomonas citri pv. citri strain B2

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag HZS92_RS12340 Protein ID WP_230598886.1
Coordinates 2816065..2816316 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag HZS92_RS12345 Protein ID WP_040259533.1
Coordinates 2816343..2816621 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HZS92_RS12315 (HZS92_02591) 2811802..2812758 - 957 WP_011051571.1 hypothetical protein -
HZS92_RS12320 (HZS92_02592) 2812825..2813958 - 1134 Protein_2409 IS5 family transposase -
HZS92_RS12330 (HZS92_02594) 2815298..2815552 - 255 WP_223293127.1 hypothetical protein -
HZS92_RS23575 2815621..2815755 - 135 WP_011051575.1 hypothetical protein -
HZS92_RS12335 (HZS92_02595) 2815748..2816062 - 315 WP_015463310.1 hypothetical protein -
HZS92_RS12340 (HZS92_02596) 2816065..2816316 - 252 WP_230598886.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
HZS92_RS12345 (HZS92_02597) 2816343..2816621 - 279 WP_040259533.1 CopG family ribbon-helix-helix protein Antitoxin
HZS92_RS12350 (HZS92_02598) 2816791..2818059 - 1269 Protein_2416 Tn3 family transposase -
HZS92_RS12355 (HZS92_02599) 2818108..2819333 + 1226 Protein_2417 IS3 family transposase -
HZS92_RS12360 (HZS92_02600) 2819970..2820677 + 708 Protein_2418 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2808235..2834756 26521
inside IScluster/Tn - - 2812825..2819333 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9519.85 Da        Isoelectric Point: 10.2314

>T169665 WP_230598886.1 NZ_CP059999:c2816316-2816065 [Xanthomonas citri pv. citri]
MQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T169665 NZ_CP076654:261549-261779 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10829.16 Da        Isoelectric Point: 4.9801

>AT169665 WP_040259533.1 NZ_CP059999:c2816621-2816343 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLRVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT169665 NZ_CP076654:261776-262135 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References