Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 3162518..3163074 Replicon chromosome
Accession NZ_CP018854
Organism Xanthomonas citri pv. citri strain LH276

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BI316_RS14415 Protein ID WP_011051576.1
Coordinates 3162518..3162808 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag BI316_RS14420 Protein ID WP_004541313.1
Coordinates 3162796..3163074 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI316_RS26460 3158255..3159211 - 957 WP_011051571.1 hypothetical protein -
BI316_RS14390 3159278..3160411 - 1134 Protein_2661 IS5 family transposase -
BI316_RS14395 3160451..3161538 - 1088 Protein_2662 IS3 family transposase -
BI316_RS14405 3161751..3161930 - 180 WP_015463309.1 hypothetical protein -
BI316_RS14410 3162201..3162521 - 321 WP_099522003.1 hypothetical protein -
BI316_RS14415 3162518..3162808 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BI316_RS14420 3162796..3163074 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
BI316_RS14425 3163244..3164512 - 1269 Protein_2667 transposase -
BI316_RS14435 3164561..3165786 + 1226 Protein_2668 IS3 family transposase -
BI316_RS14440 3166422..3167360 + 939 WP_043930788.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 3154688..3181208 26520
inside IScluster/Tn - - 3159278..3165786 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T70714 WP_011051576.1 NZ_CP018854:c3162808-3162518 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T70714 NZ_CP018854:c3162808-3162518 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT70714 WP_004541313.1 NZ_CP018854:c3163074-3162796 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT70714 NZ_CP018854:c3163074-3162796 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References