70699

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2663199..2663755 Replicon chromosome
Accession NZ_CP018847
Organism Xanthomonas citri pv. citri strain LL074-4

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BI314_RS11880 Protein ID WP_011051576.1
Coordinates 2663465..2663755 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag BI314_RS11875 Protein ID WP_004541313.1
Coordinates 2663199..2663477 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BI314_RS11855 2658913..2659851 - 939 WP_043930788.1 recombinase family protein -
BI314_RS11860 2660487..2661712 - 1226 Protein_2175 IS3 family transposase -
BI314_RS11870 2661761..2663029 + 1269 Protein_2176 transposase -
BI314_RS11875 2663199..2663477 + 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
BI314_RS11880 2663465..2663755 + 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BI314_RS11885 2663752..2664072 + 321 WP_099522003.1 hypothetical protein -
BI314_RS11890 2664343..2664522 + 180 WP_015463309.1 hypothetical protein -
BI314_RS11900 2664735..2665822 + 1088 Protein_2181 IS3 family transposase -
BI314_RS11905 2665862..2666995 + 1134 Protein_2182 IS5 family transposase -
BI314_RS25205 2667287..2667480 + 194 Protein_2183 hypothetical protein -
BI314_RS11910 2667587..2667955 - 369 WP_015472110.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2645661..2673577 27916
inside IScluster/Tn - - 2660487..2666995 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T70699 WP_011051576.1 NZ_CP018847:2663465-2663755 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T70699 NZ_CP018847:2663465-2663755 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT70699 WP_004541313.1 NZ_CP018847:2663199-2663477 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT70699 NZ_CP018847:2663199-2663477 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References