Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2893779..2894335 Replicon chromosome
Accession NZ_CP075325
Organism Xanthomonas citri pv. citri strain GD82

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag KJA71_RS12830 Protein ID WP_230598886.1
Coordinates 2893779..2894030 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag KJA71_RS12835 Protein ID WP_004541313.1
Coordinates 2894057..2894335 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KJA71_RS12805 (KJA71_12805) 2889516..2890472 - 957 WP_011051571.1 hypothetical protein -
KJA71_RS12810 (KJA71_12810) 2890539..2891672 - 1134 Protein_2512 IS5 family transposase -
KJA71_RS12820 (KJA71_12820) 2893012..2893266 - 255 WP_223293127.1 hypothetical protein -
KJA71_RS24750 2893335..2893469 - 135 WP_011051575.1 hypothetical protein -
KJA71_RS12825 (KJA71_12825) 2893462..2893776 - 315 WP_015463310.1 hypothetical protein -
KJA71_RS12830 (KJA71_12830) 2893779..2894030 - 252 WP_230598886.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KJA71_RS12835 (KJA71_12835) 2894057..2894335 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
KJA71_RS12840 (KJA71_12840) 2894505..2895773 - 1269 Protein_2519 Tn3 family transposase -
KJA71_RS12845 (KJA71_12845) 2895822..2897047 + 1226 Protein_2520 IS3 family transposase -
KJA71_RS12850 (KJA71_12850) 2897683..2898390 + 708 Protein_2521 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2885949..2912469 26520
inside IScluster/Tn - - 2890539..2897047 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-81)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 9519.85 Da        Isoelectric Point: 10.2314

>T203456 WP_230598886.1 NZ_CP075325:c2894030-2893779 [Xanthomonas citri pv. citri]
MQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAGDTVTILAVRHQKE
AGY

Download         Length: 252 bp

>T203456 NZ_CP100094:c2736988-2735666 [Klebsiella pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCACCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACTCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCGGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT203456 WP_004541313.1 NZ_CP075325:c2894335-2894057 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT203456 NZ_CP100094:c2737254-2736988 [Klebsiella pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGATGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References