Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2817563..2818119 Replicon chromosome
Accession NZ_CP008989
Organism Xanthomonas citri pv. citri strain UI7

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AMD18_RS12785 Protein ID WP_011051576.1
Coordinates 2817563..2817853 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag AMD18_RS12790 Protein ID WP_004541313.1
Coordinates 2817841..2818119 (-) Length 93 a.a.

Genomic Context

AMD18_RS12805AMD18_RS12810AMD18_RS25050AMD18_RS12760AMD18_RS12765AMD18_RS12775AMD18_RS12780AMD18_RS12785AMD18_RS12790AMD18_RS12795
Location: 2819606..2820831 (1226 bp)
Type: Others
Protein ID: Protein_2409
Location: 2821451..2822407 (957 bp)
Type: Others
Protein ID: WP_015463313.1
Location: 2813300..2814256 (957 bp)
Type: Others
Protein ID: WP_011051571.1
Location: 2814323..2815456 (1134 bp)
Type: Others
Protein ID: Protein_2402
Location: 2815496..2816583 (1088 bp)
Type: Others
Protein ID: Protein_2403
Location: 2816796..2816975 (180 bp)
Type: Others
Protein ID: WP_015463309.1
Location: 2817246..2817560 (315 bp)
Type: Others
Protein ID: WP_015463310.1
Location: 2817563..2817853 (291 bp)
Type: Toxin
Protein ID: WP_011051576.1
Location: 2817841..2818119 (279 bp)
Type: Antitoxin
Protein ID: WP_004541313.1
Location: 2818289..2819557 (1269 bp)
Type: Others
Protein ID: Protein_2408
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
AMD18_RS250502813300..2814256-957WP_011051571.1hypothetical protein-
AMD18_RS127602814323..2815456-1134Protein_2402IS5 family transposase-
AMD18_RS127652815496..2816583-1088Protein_2403IS3 family transposase-
AMD18_RS127752816796..2816975-180WP_015463309.1hypothetical protein-
AMD18_RS127802817246..2817560-315WP_015463310.1hypothetical protein-
AMD18_RS127852817563..2817853-291WP_011051576.1type II toxin-antitoxin system RelE/ParE family toxinToxin
AMD18_RS127902817841..2818119-279WP_004541313.1CopG family ribbon-helix-helix proteinAntitoxin
AMD18_RS127952818289..2819557-1269Protein_2408transposase-
AMD18_RS128052819606..2820831+1226Protein_2409IS3 family transposase-
AMD18_RS128102821451..2822407+957WP_015463313.1recombinase family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
insideGenomic island--2809733..283625526522
insideIScluster/Tn--2814323..28208316508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T48010 WP_011051576.1 NZ_CP008989:c2817853-2817563 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T48010 NZ_CP008989:c2817853-2817563 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT48010 WP_004541313.1 NZ_CP008989:c2818119-2817841 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT48010 NZ_CP008989:c2818119-2817841 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBM4UBZ0

References