Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2433579..2434135 Replicon chromosome
Accession NZ_CP060465
Organism Xanthomonas citri pv. citri strain DAR73886

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag H8Z71_RS10330 Protein ID WP_011051576.1
Coordinates 2433579..2433869 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag H8Z71_RS10335 Protein ID WP_004541313.1
Coordinates 2433857..2434135 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
H8Z71_RS10305 2429316..2430272 - 957 WP_011051571.1 hypothetical protein -
H8Z71_RS10310 2430339..2431472 - 1134 Protein_2021 IS5 family transposase -
H8Z71_RS10315 2431512..2432599 - 1088 Protein_2022 IS3 family transposase -
H8Z71_RS10320 2432812..2432991 - 180 WP_015463309.1 hypothetical protein -
H8Z71_RS10325 2433262..2433576 - 315 WP_015463310.1 hypothetical protein -
H8Z71_RS10330 2433579..2433869 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
H8Z71_RS10335 2433857..2434135 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
H8Z71_RS10340 2434305..2435573 - 1269 Protein_2027 transposase -
H8Z71_RS10345 2435622..2436847 + 1226 Protein_2028 IS3 family transposase -
H8Z71_RS10350 2437466..2438422 + 957 WP_197707729.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2423765..2445242 21477
inside IScluster/Tn - - 2430339..2436847 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T170441 WP_011051576.1 NZ_CP060465:c2433869-2433579 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T170441 NZ_CP077373:c15964-15644 [Acinetobacter lwoffii]
ATGTTATTCATTGAAACCAGTATTTTTACCAAGCAAATCAAAGAACTTGTGAGTGATAAAGAGTATCGTCAGCTCCAGCA
AGATCTCTTGGTACAGCCTGATAAGGGCGACTTAATCAAGAATGGCGGAGGTATTCGTAAAGTACGTTGTGCTCAAGGTA
ACAAGGGTAAAAGTGGCGGTATCCGTGTGATCTACTATTGGGTCACAGAAGATGATCAGATCTTTTTCTTGGTAGCTTAT
CCAAAGTCTGTGAAAGACAATCTGACTGATAAAGAGACCTCGATCCTGCGTCAATTAGTGAAGGAGCAATTTCATGGATA
A

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT170441 WP_004541313.1 NZ_CP060465:c2434135-2433857 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT170441 NZ_CP077373:c15651-15379 [Acinetobacter lwoffii]
ATGGATAACAGCTTATTTGATGACCTGGTTGCTTCAATTAAAGAAGCTGGTGCTATCAAACGTAATGAGATAAAGGCAAG
TCGAGTCACAGAGCTTGAATTGCCGGATATTAAGGAAGTACGTGAGAAAACTGGCTTAACCCAGGCAGAATTTGCTGCAC
GTTTGCATATCAGCGCGAGAACCCTGCAAAACTGGGAGCAAGGTCGTCGCTATCCGACTGGCCCTGCAGCGACTCTAATT
CGCATTCTGGATGCCCATCCAACCCTAATTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References