75625

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1928672..1929228 Replicon chromosome
Accession NZ_CP020885
Organism Xanthomonas citri pv. citri strain TX160149

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag B7L66_RS08685 Protein ID WP_011051576.1
Coordinates 1928938..1929228 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag B7L66_RS08680 Protein ID WP_004541313.1
Coordinates 1928672..1928950 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L66_RS08665 1924440..1925665 - 1226 Protein_1613 IS3 family transposase -
B7L66_RS08670 1925714..1926913 + 1200 Protein_1614 transposase -
B7L66_RS08675 1927032..1928408 + 1377 WP_011347842.1 IS5-like element ISXca5 family transposase -
B7L66_RS08680 1928672..1928950 + 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
B7L66_RS08685 1928938..1929228 + 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B7L66_RS08690 1929225..1929545 + 321 WP_099522003.1 hypothetical protein -
B7L66_RS08695 1929816..1929995 + 180 WP_015463309.1 hypothetical protein -
B7L66_RS08700 1930208..1931295 + 1088 Protein_1620 IS3 family transposase -
B7L66_RS08705 1931335..1932468 + 1134 Protein_1621 IS5 family transposase -
B7L66_RS08710 1932760..1932953 + 194 Protein_1622 hypothetical protein -
B7L66_RS08715 1933060..1933428 - 369 WP_015472110.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 1909504..1939050 29546
inside IScluster/Tn - - 1924440..1932468 8028


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T75625 WP_011051576.1 NZ_CP020885:1928938-1929228 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T75625 NZ_CP020885:1928938-1929228 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT75625 WP_004541313.1 NZ_CP020885:1928672-1928950 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT75625 NZ_CP020885:1928672-1928950 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References