Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2827870..2828426 Replicon chromosome
Accession NZ_CP023661
Organism Xanthomonas citri pv. citri strain Xcc29-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag COR42_RS12955 Protein ID WP_011051576.1
Coordinates 2827870..2828160 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag COR42_RS12960 Protein ID WP_004541313.1
Coordinates 2828148..2828426 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
COR42_RS24380 2823607..2824563 - 957 WP_011051571.1 hypothetical protein -
COR42_RS12935 2824630..2825763 - 1134 Protein_2405 IS5 family transposase -
COR42_RS12940 2825803..2826890 - 1088 Protein_2406 IS3 family transposase -
COR42_RS12945 2827103..2827282 - 180 WP_015463309.1 hypothetical protein -
COR42_RS12950 2827553..2827867 - 315 WP_015463310.1 hypothetical protein -
COR42_RS12955 2827870..2828160 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
COR42_RS12960 2828148..2828426 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
COR42_RS12965 2828596..2829864 - 1269 Protein_2411 transposase -
COR42_RS12970 2829913..2831138 + 1226 Protein_2412 IS3 family transposase -
COR42_RS12975 2831757..2832713 + 957 WP_015463313.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2820040..2846560 26520
inside IScluster/Tn - - 2824630..2831138 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T85837 WP_011051576.1 NZ_CP023661:c2828160-2827870 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T85837 NZ_CP023661:c2828160-2827870 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT85837 WP_004541313.1 NZ_CP023661:c2828426-2828148 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT85837 NZ_CP023661:c2828426-2828148 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References