Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2828313..2828869 Replicon chromosome
Accession NZ_CP009007
Organism Xanthomonas citri pv. citri strain MF20

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AMD10_RS12800 Protein ID WP_011051576.1
Coordinates 2828313..2828603 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag AMD10_RS12805 Protein ID WP_004541313.1
Coordinates 2828591..2828869 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD10_RS25260 2824050..2825006 - 957 WP_011051571.1 hypothetical protein -
AMD10_RS12775 2825073..2826206 - 1134 Protein_2412 IS5 family transposase -
AMD10_RS12780 2826246..2827333 - 1088 Protein_2413 IS3 family transposase -
AMD10_RS12790 2827546..2827725 - 180 WP_015463309.1 hypothetical protein -
AMD10_RS12795 2827996..2828310 - 315 WP_015463310.1 hypothetical protein -
AMD10_RS12800 2828313..2828603 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AMD10_RS12805 2828591..2828869 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
AMD10_RS12810 2829039..2830307 - 1269 Protein_2418 transposase -
AMD10_RS12820 2830356..2831581 + 1226 Protein_2419 IS3 family transposase -
AMD10_RS12825 2832199..2833155 + 957 WP_197707729.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2820483..2847003 26520
inside IScluster/Tn - - 2825073..2831581 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T48058 WP_011051576.1 NZ_CP009007:c2828603-2828313 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T48058 NZ_CP009007:c2828603-2828313 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT48058 WP_004541313.1 NZ_CP009007:c2828869-2828591 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT48058 NZ_CP009007:c2828869-2828591 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References