Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2828314..2828870 Replicon chromosome
Accession NZ_CP006857
Organism Xanthomonas citri subsp. citri A306

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag J151_RS12850 Protein ID WP_011051576.1
Coordinates 2828314..2828604 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag J151_RS12855 Protein ID WP_004541313.1
Coordinates 2828592..2828870 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J151_RS25390 2824051..2825007 - 957 WP_011051571.1 hypothetical protein -
J151_RS12825 2825074..2826207 - 1134 Protein_2411 IS5 family transposase -
J151_RS12830 2826247..2827334 - 1088 Protein_2412 IS3 family transposase -
J151_RS12840 2827547..2827726 - 180 WP_015463309.1 hypothetical protein -
J151_RS12845 2827997..2828317 - 321 WP_099522003.1 hypothetical protein -
J151_RS12850 2828314..2828604 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J151_RS12855 2828592..2828870 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
J151_RS12860 2829040..2830308 - 1269 Protein_2417 transposase -
J151_RS12870 2830357..2831582 + 1226 Protein_2418 IS3 family transposase -
J151_RS12875 2832218..2833156 + 939 WP_043930788.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2820484..2847004 26520
inside IScluster/Tn - - 2825074..2831582 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T45715 WP_011051576.1 NZ_CP006857:c2828604-2828314 [Xanthomonas citri subsp. citri A306]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T45715 NZ_CP006857:c2828604-2828314 [Xanthomonas citri subsp. citri A306]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT45715 WP_004541313.1 NZ_CP006857:c2828870-2828592 [Xanthomonas citri subsp. citri A306]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT45715 NZ_CP006857:c2828870-2828592 [Xanthomonas citri subsp. citri A306]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References