Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2308502..2309058 Replicon chromosome
Accession NZ_CP009034
Organism Xanthomonas citri pv. citri strain AW14

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AMD08_RS10450 Protein ID WP_011051576.1
Coordinates 2308502..2308792 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag AMD08_RS10455 Protein ID WP_004541313.1
Coordinates 2308780..2309058 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD08_RS26090 2304239..2305195 - 957 WP_011051571.1 hypothetical protein -
AMD08_RS10425 2305262..2306395 - 1134 Protein_1970 IS5 family transposase -
AMD08_RS10430 2306435..2307522 - 1088 Protein_1971 IS3 family transposase -
AMD08_RS10440 2307735..2307914 - 180 WP_015463309.1 hypothetical protein -
AMD08_RS10445 2308185..2308499 - 315 WP_015463310.1 hypothetical protein -
AMD08_RS10450 2308502..2308792 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AMD08_RS10455 2308780..2309058 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
AMD08_RS10460 2309228..2310496 - 1269 Protein_1976 transposase -
AMD08_RS10470 2310545..2311770 + 1226 Protein_1977 IS3 family transposase -
AMD08_RS10475 2312389..2313345 + 957 WP_015472114.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2300672..2327201 26529
inside IScluster/Tn - - 2305262..2311770 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T48128 WP_011051576.1 NZ_CP009034:c2308792-2308502 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T48128 NZ_CP009034:c2308792-2308502 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT48128 WP_004541313.1 NZ_CP009034:c2309058-2308780 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT48128 NZ_CP009034:c2309058-2308780 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGCGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References