Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2424379..2424935 Replicon chromosome
Accession NZ_CP020882
Organism Xanthomonas citri pv. citri strain TX160042

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag B7L65_RS10930 Protein ID WP_011051576.1
Coordinates 2424645..2424935 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag B7L65_RS10925 Protein ID WP_004541313.1
Coordinates 2424379..2424657 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L65_RS10905 2420147..2421372 - 1226 Protein_2030 IS3 family transposase -
B7L65_RS10910 2421421..2422203 + 783 Protein_2031 Tn3 family transposase -
B7L65_RS10915 2422319..2423695 + 1377 WP_011347842.1 IS5-like element ISXca5 family transposase -
B7L65_RS10920 2423718..2424209 + 492 Protein_2033 Tn3 family transposase -
B7L65_RS10925 2424379..2424657 + 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
B7L65_RS10930 2424645..2424935 + 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B7L65_RS10935 2424932..2425252 + 321 WP_099522003.1 hypothetical protein -
B7L65_RS10940 2425523..2425702 + 180 WP_015463309.1 hypothetical protein -
B7L65_RS10945 2425915..2427002 + 1088 Protein_2038 IS3 family transposase -
B7L65_RS10950 2427042..2428175 + 1134 Protein_2039 IS5 family transposase -
B7L65_RS10955 2428467..2428660 + 194 Protein_2040 hypothetical protein -
B7L65_RS10960 2428767..2429135 - 369 WP_015472110.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2403293..2434757 31464
inside IScluster/Tn - - 2420147..2428175 8028


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T75621 WP_011051576.1 NZ_CP020882:2424645-2424935 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T75621 NZ_CP020882:2424645-2424935 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT75621 WP_004541313.1 NZ_CP020882:2424379-2424657 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT75621 NZ_CP020882:2424379-2424657 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGCGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References