Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 4037579..4038135 Replicon chromosome
Accession NZ_CP020889
Organism Xanthomonas citri pv. citri strain TX160197

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag B7L67_RS18410 Protein ID WP_011051576.1
Coordinates 4037845..4038135 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag B7L67_RS18405 Protein ID WP_004541313.1
Coordinates 4037579..4037857 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7L67_RS18385 4033347..4034572 - 1226 Protein_3410 IS3 family transposase -
B7L67_RS18390 4034621..4035403 + 783 Protein_3411 Tn3 family transposase -
B7L67_RS18395 4035519..4036895 + 1377 WP_011347842.1 IS5-like element ISXca5 family transposase -
B7L67_RS18400 4036918..4037409 + 492 Protein_3413 Tn3 family transposase -
B7L67_RS18405 4037579..4037857 + 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
B7L67_RS18410 4037845..4038135 + 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B7L67_RS18415 4038138..4038452 + 315 WP_015463310.1 hypothetical protein -
B7L67_RS18420 4038723..4038902 + 180 WP_015463309.1 hypothetical protein -
B7L67_RS18425 4039115..4040202 + 1088 Protein_3418 IS3 family transposase -
B7L67_RS18430 4040242..4041375 + 1134 Protein_3419 IS5 family transposase -
B7L67_RS26230 4041442..4042398 + 957 WP_011051571.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 4016493..4047957 31464
inside IScluster/Tn - - 4033347..4041375 8028


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T75638 WP_011051576.1 NZ_CP020889:4037845-4038135 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T75638 NZ_CP020889:4037845-4038135 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT75638 WP_004541313.1 NZ_CP020889:4037579-4037857 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT75638 NZ_CP020889:4037579-4037857 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGCGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References