Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2828319..2828875 Replicon chromosome
Accession NZ_CP008995
Organism Xanthomonas citri pv. citri strain NT17

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag AMD13_RS12815 Protein ID WP_011051576.1
Coordinates 2828319..2828609 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag AMD13_RS12820 Protein ID WP_004541313.1
Coordinates 2828597..2828875 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AMD13_RS24915 2823630..2823770 - 141 WP_157860651.1 hypothetical protein -
AMD13_RS25270 2824056..2825012 - 957 WP_011051571.1 hypothetical protein -
AMD13_RS12790 2825079..2826212 - 1134 Protein_2413 IS5 family transposase -
AMD13_RS12795 2826252..2827339 - 1088 Protein_2414 IS3 family transposase -
AMD13_RS12805 2827552..2827731 - 180 WP_015463309.1 hypothetical protein -
AMD13_RS12810 2828002..2828316 - 315 WP_015463310.1 hypothetical protein -
AMD13_RS12815 2828319..2828609 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AMD13_RS12820 2828597..2828875 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
AMD13_RS12825 2829045..2830313 - 1269 Protein_2419 transposase -
AMD13_RS12835 2830362..2831587 + 1226 Protein_2420 IS3 family transposase -
AMD13_RS12840 2832205..2833161 + 957 WP_197707729.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2820489..2847009 26520
inside IScluster/Tn - - 2825079..2831587 6508


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T48026 WP_011051576.1 NZ_CP008995:c2828609-2828319 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T48026 NZ_CP008995:c2828609-2828319 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT48026 WP_004541313.1 NZ_CP008995:c2828875-2828597 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT48026 NZ_CP008995:c2828875-2828597 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References