80707

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2944463..2945019 Replicon chromosome
Accession NZ_CP023285
Organism Xanthomonas citri pv. citri strain 03-1638-1-1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CLM98_RS13500 Protein ID WP_011051576.1
Coordinates 2944463..2944753 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID M4UBZ0
Locus tag CLM98_RS13505 Protein ID WP_004541313.1
Coordinates 2944741..2945019 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CLM98_RS25675 2940200..2941156 - 957 WP_011051571.1 hypothetical protein -
CLM98_RS13480 2941223..2942356 - 1134 Protein_2510 IS5 family transposase -
CLM98_RS13485 2942396..2943483 - 1088 Protein_2511 IS3 family transposase -
CLM98_RS13490 2943696..2943875 - 180 WP_015463309.1 hypothetical protein -
CLM98_RS13495 2944146..2944460 - 315 WP_015463310.1 hypothetical protein -
CLM98_RS13500 2944463..2944753 - 291 WP_011051576.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CLM98_RS13505 2944741..2945019 - 279 WP_004541313.1 CopG family ribbon-helix-helix protein Antitoxin
CLM98_RS13510 2945193..2946458 - 1266 Protein_2516 transposase -
CLM98_RS13515 2946507..2947732 + 1226 Protein_2517 IS3 family transposase -
CLM98_RS13520 2948350..2949306 + 957 WP_197707729.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Genomic island - - 2936632..2963154 26522
inside IScluster/Tn - - 2941223..2947732 6509


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10831.41 Da        Isoelectric Point: 9.9308

>T80707 WP_011051576.1 NZ_CP023285:c2944753-2944463 [Xanthomonas citri pv. citri]
MPQVIFAPAAIGDMQRLREFLKPKSPDAARRAGEAIRRGVQALGAHPRMGRLIEDLPEQYREWLIDFGDSGYVARYRHAG
DTVTILAVRHQKEAGY

Download         Length: 291 bp

>T80707 NZ_CP023285:c2944753-2944463 [Xanthomonas citri pv. citri]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCAACGGCTGCGCGAATTCCTGAAGCCGAAGAGTCCCGA
TGCCGCGAGGCGGGCCGGTGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGCCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGTGGCTATGTGGCTCGGTACCGCCACGCTGGC
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10810.11 Da        Isoelectric Point: 4.9736

>AT80707 WP_004541313.1 NZ_CP023285:c2945019-2944741 [Xanthomonas citri pv. citri]
MVTATSIKLDDELKGRVQHLAEARRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Download         Length: 279 bp

>AT80707 NZ_CP023285:c2945019-2944741 [Xanthomonas citri pv. citri]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCCGAGGCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGTGAGGCGTTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACGGGCCTGCACGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACAGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB M4UBZ0

References