Regulators of regulatory pathway: TCS regulatory pathway

All displayed regulators are experimentally validated.


Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
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Regulator ID
Locus tag (Gene)
Related T6SS
Regulator type
Regulatory pathway
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Target (Regulation)
REG0005 experimentalRT90_16255 (wecG)T6SS01264 experimentalproteinTCS regulatory pathwaySerratia marcescens strain RM66262chromosome (JWLO01000003)92056..92796 (-)735005313RT90_01105 (rcsC) (↑)
REG0013 experimentalY880_03649 (suhB)T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimentalproteinTCS regulatory pathwayPseudomonas aeruginosa PAKchromosome (NZ_CP020659)3616623..3617438 (+)489183406Y880_02189 (gacA/uvrY) (↓)
REG0086 experimentalexoRT6SS00016 experimentalproteinTCS regulatory pathwayAgrobacterium fabrum str. C58chromosome (NC_003062)1702398..1703192 (-)chvG (↑)
REG0173 experimentalFTN_RS06610 (mglA)T6SS00158 experimentalproteinTCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)1362282..1362899 (+)489124662iglC transcription (↓); Unknown (↓)
REG0174 experimentalFTN_RS02845 (SspA)T6SS00158 experimentalproteinTCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)574840..575472 (+)500053699FTN_1465 (pmrA) (↓)
REG0176 experimentalFTN_1465 (pmrA)T6SS00158 experimentalproteinTCS-RR; TCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)1553358..1554044 (-)489108239FTN_1465 (pmrA) promotor (↓); pdpD promotor (↓); IglA expression (↓)
REG0177 experimentalFTN_RS06615 (mglB)T6SS00158 experimentalproteinGlobal regulator; TCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)1362901..1363308 (+)489112095IglA expression (↓); T6SS Transciption (↓)
REG0178 experimentalFTN_0480 (fevR/PigR)T6SS00158 experimentalproteinTCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)486541..486876 (+)489108070T6SS Transciption (↓)
REG0205 experimentalNT01EI_RS04200 (EsrC)T6SS00346 experimentalproteinTCS regulatory pathwayEdwardsiella ictaluri 93-146chromosome (NC_012779)933326..934018 (-)737638726T6SS translocon protein EvpC secretion (↓)
REG0206 experimentalETAE_2873 (RpoS)T6SS00372 experimentalproteinTCS regulatory pathwayEdwardsiella tarda EIB202chromosome (NC_013508)3025094..3026080 (-)502612732ETAE_0886 (esrB) promoter (↑)
Showing 1 to 10 of 48 rows
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Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
JSONXMLCSVTXTSQLMS-Excel
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Regulator ID
Locus tag (Gene)
Related T6SS
Regulator type
Regulatory pathway
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Target (Regulation)
REG0005 experimentalRT90_16255 (wecG)T6SS01264 experimentalproteinTCS regulatory pathwaySerratia marcescens strain RM66262chromosome (JWLO01000003)92056..92796 (-)735005313RT90_01105 (rcsC) (↑)
REG0013 experimentalY880_03649 (suhB)T6SS01211 experimental; T6SS01212 experimental; T6SS01213 experimentalproteinTCS regulatory pathwayPseudomonas aeruginosa PAKchromosome (NZ_CP020659)3616623..3617438 (+)489183406Y880_02189 (gacA/uvrY) (↓)
REG0086 experimentalexoRT6SS00016 experimentalproteinTCS regulatory pathwayAgrobacterium fabrum str. C58chromosome (NC_003062)1702398..1703192 (-)chvG (↑)
REG0173 experimentalFTN_RS06610 (mglA)T6SS00158 experimentalproteinTCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)1362282..1362899 (+)489124662iglC transcription (↓); Unknown (↓)
REG0174 experimentalFTN_RS02845 (SspA)T6SS00158 experimentalproteinTCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)574840..575472 (+)500053699FTN_1465 (pmrA) (↓)
REG0176 experimentalFTN_1465 (pmrA)T6SS00158 experimentalproteinTCS-RR; TCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)1553358..1554044 (-)489108239FTN_1465 (pmrA) promotor (↓); pdpD promotor (↓); IglA expression (↓)
REG0177 experimentalFTN_RS06615 (mglB)T6SS00158 experimentalproteinGlobal regulator; TCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)1362901..1363308 (+)489112095IglA expression (↓); T6SS Transciption (↓)
REG0178 experimentalFTN_0480 (fevR/PigR)T6SS00158 experimentalproteinTCS regulatory pathwayFrancisella tularensis subsp. novicida U112chromosome (NC_008601)486541..486876 (+)489108070T6SS Transciption (↓)
REG0205 experimentalNT01EI_RS04200 (EsrC)T6SS00346 experimentalproteinTCS regulatory pathwayEdwardsiella ictaluri 93-146chromosome (NC_012779)933326..934018 (-)737638726T6SS translocon protein EvpC secretion (↓)
REG0206 experimentalETAE_2873 (RpoS)T6SS00372 experimentalproteinTCS regulatory pathwayEdwardsiella tarda EIB202chromosome (NC_013508)3025094..3026080 (-)502612732ETAE_0886 (esrB) promoter (↑)
Showing 1 to 10 of 48 rows
102550
 rows per page

Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negative regulation.
experimental Experimental investigation has been performed.
insolico Bioinformatics investigation has been performed
JSONXMLCSVTXTSQLMS-Excel
Loading, please wait
Regulator ID
Locus tag (Gene)
Related T6SS
Regulator type
Regulatory pathway
Organism                
Replicon (Accession)
Coordinates (Strand)
NCBI ID
Target (Regulation)
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