Detailed information of regulator


Summary

Regulator ID REG0174 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) -
Related T6SS T6SS00158 experimental (Type ii)
Strain Francisella tularensis subsp. novicida U112
Replicon chromosome
Sequence Protein sequence (211 a.a.); Nucleotide sequence (633 bp)
Description PmrA, MglA, and SspA are parts of the same protein complex.
Reference
External database links

Locus tag (Gene) FTN_RS02845 (SspA)
Coordinates (Strand) 574840..575472 (+)
NCBI ID 500053699
RefSeq NC_008601
Uniprot ID UPI0000E89329
KEGG ID -
KEGG pathway (determined by BlastKOALA) -
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
FTN_1465 (pmrA) ↓ 489108239
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
GST_C PF00043.27 8.8e-10 111..187
GST_N_3 PF13417.8 2.8e-08 6..78
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-210 MMKVTLYTTKYCPYSLRARIALAEKKMSTDIVEAGDLEPAMIKKIAPNGVFPVLMEKDYSINNRKALLIYIDERFPAPSLLPNVVNERIKIRLSLDKIDNEWYPVLDQIRKHRSDQKMLESMFKDLKESLLAMEKAFTGSEFFISSGFTLADCYIAALIICLEAEGFIIDDEYGAIYEYKKRLFARDSVKKANIKGGAGESLLKTLRAHR


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9517 - -


  Protein sequence of regulator: 211 a.a.    .

>REG0174 NC_008601:574840-575472 [Francisella tularensis subsp. novicida U112]
MMKVTLYTTKYCPYSLRARIALAEKKMSTDIVEAGDLEPAMIKKIAPNGVFPVLMEKDYSINNRKALLIYIDERFPAPSL
LPNVVNERIKIRLSLDKIDNEWYPVLDQIRKHRSDQKMLESMFKDLKESLLAMEKAFTGSEFFISSGFTLADCYIAALII
CLEAEGFIIDDEYGAIYEYKKRLFARDSVKKANIKGGAGESLLKTLRAHR*

  Nucleotide sequence of regulator: 633 bp    .

>REG0174 NC_008601:574840-575472 [Francisella tularensis subsp. novicida U112]
TTGATGAAAGTTACATTATATACAACGAAGTATTGTCCATATTCTCTTAGAGCAAGAATTGCTTTAGCAGAAAAGAAAAT
GTCAACAGATATCGTAGAGGCTGGCGACTTAGAACCAGCTATGATCAAGAAAATAGCTCCTAATGGTGTTTTCCCTGTTT
TGATGGAGAAAGACTATAGCATCAATAATAGAAAAGCATTGCTAATTTATATTGATGAAAGATTTCCTGCGCCAAGCTTG
CTACCAAATGTAGTTAATGAGCGCATAAAGATACGCTTATCGCTTGATAAAATTGATAATGAGTGGTATCCAGTATTAGA
TCAAATTCGCAAACACAGATCAGATCAGAAGATGCTTGAATCAATGTTTAAAGACCTAAAAGAAAGTTTATTGGCAATGG
AAAAAGCTTTTACTGGCTCAGAGTTTTTTATATCTTCTGGCTTTACTTTAGCAGATTGTTATATAGCTGCTTTGATTATA
TGTTTAGAAGCAGAAGGATTTATTATTGATGATGAATATGGGGCAATTTATGAGTATAAAAAAAGACTCTTTGCTAGAGA
TTCGGTCAAAAAAGCTAACATAAAAGGCGGCGCTGGTGAGTCATTACTCAAAACTCTAAGAGCTCATAGATAA