Detailed information of regulator


Summary

Regulator ID REG0223 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) Metabolic pathways (map01100); Biosynthesis of secondary metabolites (map01110); Microbial metabolism in diverse environments (map01120); Carbon metabolism (map01200); Glycolysis / Gluconeogenesis (map00010); Citrate cycle (TCA cycle) (map00020); Pyruvate metabolism (map00620)
Related T6SS T6SS00372 experimental (Type i4b)
Strain Edwardsiella tarda EIB202
Replicon chromosome
Sequence Protein sequence (888 a.a.); Nucleotide sequence (2664 bp)
Description Putative repressors of esrB as identified by Tn-seq.
Reference
External database links

Locus tag (Gene) ETAE_0659 (aceE)
Coordinates (Strand) 731608..734271 (+)
NCBI ID 502610523
RefSeq NC_013508
Uniprot ID D0ZCM5_EDWTE, A0A0H3DMY7_EDWTF
KEGG ID etd:ETAF_0604, etr:ETAE_0659
KEGG pathway (determined by BlastKOALA) map01100; map01110; map01120; map01200; map00010; map00020; map00620
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
ETAE_0886 (esrB) promoter ↑ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
PDH_E1_M PF17831.3 1.9e-102 487..700
Transketolase_N PF00456.23 1.5e-09 106..296
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-887 MSDRLLNDVDPIETRDWLQAIESVIREEGVERAQYLIDQVLNSARQGGVNLPSAALAHNYVNTIAPEDEPAYPGNLELERRIRIAMRWNAVMIVLHASKKDLELGGHMASYQSSATVYEVCFNHFFRARNQKDGGDLVYFQGHISPGIYARAFLEGRLTEEQLNNFRQEVHGTGLSSYPHPKLMPEFWQFPTVSMGLGPLGAIYQAKFLKYLNHRGLKDTTAQRVYAFLGDGEMDEPESKGAITIATRDKLDNLCFVINCNLQRLDGPVTGNGKIINELEGIFAGAGWNVIKVIWGSRWDALLRKDTSGKLIQLMNETLDGDYQTFKSKNGAYVREHFFGRYPETAALVKDMSDDEIWALNRGGHDPKKVYAAFKKAEETKGQPTVILVHTIKGYGMGDTAEGKNIAHQVKKMNMDGVRHFRDRFNVPVADADLEKLPYVTFDADSEEARYLHERRAALQGYVPTRSPTFSERLELPALEDFSALLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQRYTPQDREQVAYYKEDEKGQILQEGINELGAGASWLAAATSYSTNDLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPQGVEEGIRRGIYKLDTQSGDKGKVQLLGSGSMLRHVREAARILSEEYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPAVASTDYMKLFAEQVRTYVPASDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGELAKRGEIAASVVADAIGKFNIDPEKVNPRLA


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9430 - -


  Protein sequence of regulator: 888 a.a.    .

>REG0223 NC_013508:731608-734271 [Edwardsiella tarda EIB202]
MSDRLLNDVDPIETRDWLQAIESVIREEGVERAQYLIDQVLNSARQGGVNLPSAALAHNYVNTIAPEDEPAYPGNLELER
RIRIAMRWNAVMIVLHASKKDLELGGHMASYQSSATVYEVCFNHFFRARNQKDGGDLVYFQGHISPGIYARAFLEGRLTE
EQLNNFRQEVHGTGLSSYPHPKLMPEFWQFPTVSMGLGPLGAIYQAKFLKYLNHRGLKDTTAQRVYAFLGDGEMDEPESK
GAITIATRDKLDNLCFVINCNLQRLDGPVTGNGKIINELEGIFAGAGWNVIKVIWGSRWDALLRKDTSGKLIQLMNETLD
GDYQTFKSKNGAYVREHFFGRYPETAALVKDMSDDEIWALNRGGHDPKKVYAAFKKAEETKGQPTVILVHTIKGYGMGDT
AEGKNIAHQVKKMNMDGVRHFRDRFNVPVADADLEKLPYVTFDADSEEARYLHERRAALQGYVPTRSPTFSERLELPALE
DFSALLEEQNKEISTTIAFVRALNVMLKNKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQRYTPQDREQVAYYKED
EKGQILQEGINELGAGASWLAAATSYSTNDLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFLIGGTSGRTTLNGEGLQ
HEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEKQENVYYYITTLNENYHMPAMPQGVEEGIRRGIYKLDTQ
SGDKGKVQLLGSGSMLRHVREAARILSEEYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPAVA
STDYMKLFAEQVRTYVPASDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGELAKRGEIAASVVADAIGKFNIDPE
KVNPRLA*

  Nucleotide sequence of regulator: 2664 bp    .

>REG0223 NC_013508:731608-734271 [Edwardsiella tarda EIB202]
ATGTCAGATCGTTTACTTAATGACGTGGATCCGATCGAAACCCGCGATTGGCTGCAGGCGATAGAATCGGTCATCCGTGA
AGAAGGCGTAGAGCGCGCGCAGTATCTGATCGATCAGGTACTGAATTCCGCCCGTCAGGGCGGCGTTAATCTGCCTTCCG
CTGCGCTGGCCCACAATTACGTGAACACCATTGCTCCGGAAGATGAGCCGGCCTATCCGGGGAATCTGGAGCTGGAGCGT
CGTATCCGCATCGCCATGCGTTGGAATGCGGTGATGATCGTCCTGCATGCGTCGAAGAAAGATCTGGAGCTGGGCGGTCA
CATGGCCTCCTATCAGTCTTCTGCGACGGTGTATGAAGTGTGCTTTAACCATTTCTTCCGCGCCCGTAACCAGAAGGACG
GCGGCGATCTGGTCTACTTCCAGGGCCATATCTCTCCGGGGATCTACGCGCGCGCCTTCCTGGAAGGACGCCTGACCGAG
GAGCAGCTGAATAACTTCCGTCAGGAGGTTCACGGCACGGGGCTCTCTTCTTACCCGCATCCGAAGCTGATGCCGGAGTT
CTGGCAGTTCCCGACCGTTTCCATGGGTCTGGGGCCGTTGGGGGCGATTTATCAGGCTAAGTTCCTGAAATACCTGAATC
ACCGCGGTCTGAAAGACACCACGGCGCAGCGCGTTTACGCCTTCCTCGGCGACGGTGAGATGGATGAGCCGGAATCCAAG
GGCGCCATCACCATCGCTACCCGCGATAAGCTGGACAACCTGTGCTTCGTCATTAACTGCAACCTGCAGCGTCTGGATGG
CCCGGTGACGGGGAACGGCAAGATCATCAACGAACTGGAAGGCATCTTCGCCGGTGCGGGCTGGAACGTGATCAAGGTGA
TTTGGGGCTCCCGCTGGGATGCGCTGCTGCGTAAAGATACCAGCGGTAAGCTGATCCAACTGATGAATGAAACCCTGGAC
GGCGACTACCAAACCTTCAAGTCAAAGAATGGCGCCTATGTGCGTGAACACTTCTTTGGCCGTTATCCGGAAACCGCGGC
GCTGGTCAAGGATATGTCTGACGATGAGATCTGGGCGCTGAACCGCGGCGGCCACGATCCGAAGAAAGTCTACGCCGCCT
TTAAGAAAGCCGAAGAGACCAAAGGTCAGCCGACGGTGATCCTGGTGCATACCATCAAGGGCTATGGCATGGGCGACACC
GCCGAAGGCAAAAACATCGCTCACCAGGTTAAGAAGATGAACATGGATGGCGTGCGCCATTTCCGCGATCGCTTCAACGT
GCCGGTGGCCGATGCCGATCTGGAGAAGCTGCCGTACGTCACCTTTGACGCCGACTCCGAAGAGGCGCGCTATCTGCATG
AGCGTCGCGCCGCGCTGCAGGGCTATGTCCCGACCCGTAGCCCGACCTTTAGCGAGCGTCTAGAACTGCCGGCGCTGGAG
GACTTCTCCGCCCTGCTGGAAGAGCAGAACAAAGAGATTTCGACCACCATCGCCTTCGTACGTGCGTTGAACGTAATGCT
GAAGAACAAGTCCATCAAGGATCGTCTGGTGCCGATCATCGCTGACGAAGCGCGTACCTTCGGTATGGAAGGGCTGTTCC
GTCAGATTGGGATCTATAGCCCGAACGGCCAGCGCTACACCCCGCAGGATCGCGAGCAGGTGGCCTACTACAAAGAAGAC
GAGAAAGGACAGATTCTGCAGGAGGGGATCAACGAGCTGGGCGCCGGGGCCTCTTGGCTGGCGGCAGCGACCTCTTACAG
CACTAACGATCTGCCGATGATCCCGTTCTACATCTACTACTCCATGTTCGGCTTCCAGCGCATCGGCGACCTGTGCTGGG
CGGCGGGCGACCAGCAGGCGCGCGGTTTCCTGATCGGCGGCACCTCTGGACGCACCACCCTGAACGGGGAAGGTCTGCAG
CACGAAGATGGCCACAGCCATATTCAGTCCCTGACTATCCCGAACTGCATCTCCTACGATCCGGCCTATGCCTATGAAGT
GGCCGTGATCATGCACGACGGTCTGGAGCGCATGTACGGTGAGAAGCAGGAGAACGTGTACTACTACATCACCACGCTGA
ACGAAAACTACCACATGCCGGCGATGCCGCAGGGCGTTGAAGAGGGCATCCGCCGCGGGATCTACAAGCTGGATACGCAG
TCCGGCGATAAGGGCAAGGTCCAGCTGCTGGGCTCCGGCTCCATGCTGCGCCACGTCCGCGAGGCCGCGCGTATTCTGTC
TGAAGAGTATGGCGTTGGCAGCGATGTGTACAGCGTGACCTCCTTCACCGAGCTGGCGCGCGATGGCCAGGACTGCGAGC
GTTGGAACATGCTGCATCCGCTGGAGACCCCGCGCGTACCGTACATCGCTCAGGTGATGAACGATGCGCCGGCCGTGGCG
TCTACCGACTATATGAAACTGTTTGCCGAGCAGGTACGTACCTATGTTCCGGCCAGCGATTACCGCGTGCTGGGCACCGA
TGGCTTCGGCCGCTCCGACAGCCGTGAAAACCTGCGTCACCACTTTGAGGTCGATGCCTCCTACGTGGTGGTGGCGGCAC
TGGGTGAACTGGCAAAACGCGGGGAGATCGCCGCTTCCGTGGTGGCGGACGCCATCGGCAAGTTCAATATCGATCCGGAA
AAAGTAAACCCGCGTCTGGCATAA