Detailed information of regulator


Summary

Regulator ID REG0235 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) Biofilm formation - Escherichia coli (map02026)
Related T6SS T6SS00372 experimental (Type i4b)
Strain Edwardsiella tarda EIB202
Replicon chromosome
Sequence Protein sequence (542 a.a.); Nucleotide sequence (1626 bp)
Description Putative activators of esrB as identified by Tn-seq.
Reference
External database links

Locus tag (Gene) ETAE_1562
Coordinates (Strand) 1668753..1670378 (-)
NCBI ID 780104675
RefSeq NC_013508
Uniprot ID UPI0002D77E6A
KEGG ID -
KEGG pathway (determined by BlastKOALA) map02026
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
ETAE_0886 (esrB) promoter ↓ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
EAL PF00563.22 2.5e-57 277..504
CSS-motif PF12792.9 6e-13 49..236
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-12 MLFSHITMKRYR
Transmembrane helix 13-35 LYRALLAITIGALVCIISLASRY
Outside 36-541 QQELTTVQQMQRNAATIAITQLERILSRAETVSKNNIGWVNQRCEEISPHLTNMAIHLETIRAVLLVKDGIVTCSNLINQPIKSLRAIYPEMLSAKDTLVLRAARLLNRGSPILLFWRPDQANPTSGMVYIFNIATLSAFILAPRPPYVDYMALNVAGHTLRFNDMRVRAPTDAAEAETPPRLELRSSRYPFSISLFSPAARDLALQRLPRHIPLALLLFLLASILTYLASANRMSLAYPIAQAIRRRQLTLYCQPIIHTESGRCEGVEILLRWYNPRHGWTSPEIFIPLAEQNGLIVPLTRYLLEALAAQRHHFPHDRDFYFSINVAAEHFAQGKLALDIQNLWLRHRPQQRLMLELTERTRLPSQDYPQLHILREMGLSLALDDFGTGHSSLSYLQDLQPEMLKIDRAFCATIGSDAINARVLDLMIDLARQLRLRLVMEGVEQTQQADYLRQRQVYAMQGYLFARPMPLRDFPGWHAHYQRQCGDSTPAAQSAGEFSRAPAQT


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8445 - -


  Protein sequence of regulator: 542 a.a.    .

>REG0235 NC_013508:c1670378-1668753 [Edwardsiella tarda EIB202]
MLFSHITMKRYRLYRALLAITIGALVCIISLASRYQQELTTVQQMQRNAATIAITQLERILSRAETVSKNNIGWVNQRCE
EISPHLTNMAIHLETIRAVLLVKDGIVTCSNLINQPIKSLRAIYPEMLSAKDTLVLRAARLLNRGSPILLFWRPDQANPT
SGMVYIFNIATLSAFILAPRPPYVDYMALNVAGHTLRFNDMRVRAPTDAAEAETPPRLELRSSRYPFSISLFSPAARDLA
LQRLPRHIPLALLLFLLASILTYLASANRMSLAYPIAQAIRRRQLTLYCQPIIHTESGRCEGVEILLRWYNPRHGWTSPE
IFIPLAEQNGLIVPLTRYLLEALAAQRHHFPHDRDFYFSINVAAEHFAQGKLALDIQNLWLRHRPQQRLMLELTERTRLP
SQDYPQLHILREMGLSLALDDFGTGHSSLSYLQDLQPEMLKIDRAFCATIGSDAINARVLDLMIDLARQLRLRLVMEGVE
QTQQADYLRQRQVYAMQGYLFARPMPLRDFPGWHAHYQRQCGDSTPAAQSAGEFSRAPAQT*

  Nucleotide sequence of regulator: 1626 bp    .

>REG0235 NC_013508:c1670378-1668753 [Edwardsiella tarda EIB202]
ATGCTTTTTTCACATATCACGATGAAACGCTATCGTTTGTATCGTGCCCTATTGGCTATCACCATCGGCGCACTCGTCTG
TATTATTTCCCTCGCCAGCCGCTATCAACAGGAGCTGACAACGGTACAACAGATGCAGCGCAACGCCGCCACGATTGCCA
TTACGCAGTTGGAAAGGATCCTGTCCCGCGCCGAGACCGTCAGTAAAAATAATATCGGCTGGGTAAATCAGCGCTGCGAA
GAAATCAGTCCGCACCTGACCAATATGGCGATACACCTGGAGACGATTCGCGCCGTACTGCTGGTAAAGGATGGCATCGT
GACCTGCTCCAATCTGATCAATCAGCCGATCAAATCCCTGCGGGCCATTTACCCCGAAATGCTATCGGCCAAAGATACGT
TGGTCCTGCGGGCGGCGCGCTTGCTTAACCGCGGTAGCCCGATCCTACTGTTCTGGCGACCGGATCAGGCCAATCCCACC
AGCGGCATGGTGTATATTTTTAATATTGCCACCCTCTCCGCCTTTATCCTGGCGCCGCGTCCGCCCTATGTCGACTACAT
GGCCCTGAATGTGGCTGGCCACACGCTGCGCTTCAACGATATGCGGGTACGGGCGCCGACCGACGCCGCGGAGGCCGAGA
CGCCGCCGCGCCTGGAGCTACGCTCCAGCCGCTACCCGTTCTCGATTTCACTGTTCTCCCCCGCCGCGCGCGATCTGGCG
CTGCAGCGCCTGCCGCGCCATATTCCATTGGCGCTGCTGCTGTTCCTGCTGGCGTCGATCCTCACCTACCTGGCATCGGC
CAATCGCATGAGTCTGGCCTATCCGATCGCCCAGGCGATCCGCCGCCGTCAGCTTACGCTGTACTGTCAGCCGATCATCC
ACACGGAAAGCGGCCGCTGCGAAGGCGTGGAGATCCTGCTGCGCTGGTATAATCCGCGTCATGGCTGGACCTCGCCGGAG
ATCTTCATTCCTCTGGCCGAACAGAATGGGCTGATCGTTCCGCTGACTCGCTACCTGCTGGAAGCGCTGGCGGCGCAGCG
CCACCATTTCCCGCACGATCGTGATTTTTACTTCAGTATTAACGTTGCGGCAGAGCATTTCGCCCAGGGCAAGCTGGCCC
TGGATATCCAGAATCTGTGGCTACGCCACCGACCTCAACAGCGCCTGATGCTGGAGCTGACGGAGCGCACGCGCCTGCCC
AGCCAGGACTATCCACAGCTGCATATCCTGCGTGAAATGGGGCTATCGCTGGCGCTGGATGACTTTGGCACCGGCCACAG
TTCGCTGAGCTACCTGCAGGATCTGCAGCCTGAAATGCTGAAAATCGATCGCGCCTTTTGCGCGACCATCGGCAGCGACG
CGATTAATGCCCGGGTCTTGGACCTGATGATCGATCTGGCGCGCCAGCTACGGCTACGCCTGGTCATGGAGGGCGTCGAA
CAGACGCAGCAGGCCGACTATCTGCGCCAGCGGCAGGTTTACGCCATGCAGGGCTATCTCTTCGCCCGGCCGATGCCGCT
GCGGGATTTCCCCGGCTGGCACGCCCACTACCAGCGGCAGTGCGGCGACTCTACGCCGGCGGCGCAAAGCGCGGGAGAGT
TCTCCCGCGCCCCGGCACAAACTTAG