Detailed information of regulator
Summary
| Regulator ID | REG0237  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | TCS regulatory pathway |
| KEGG pathway (determined by BlastKOALA) | - |
| Related T6SS | T6SS00372 (Type i4b) |
| Strain | Edwardsiella tarda EIB202 |
| Replicon | chromosome |
| Sequence | Protein sequence (364 a.a.); Nucleotide sequence (1092 bp) |
| Description | Putative activators of esrB as identified by Tn-seq. |
| Reference |
External database links
| Locus tag (Gene) | ETAE_0263 (mltC) |
| Coordinates (Strand) | 293215..294306 (-) |
| NCBI ID | 1392602598 |
| RefSeq | NC_013508 |
| Uniprot ID | - |
| KEGG ID | - |
| KEGG pathway (determined by BlastKOALA) | - |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| ETAE_0886 (esrB) promoter | ↓ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| Mltc_N | PF11873.10 | 3.9e-66 | 31..194 |
| SLT | PF01464.22 | 8.7e-33 | 199..320 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-363 | MAVTMKKVLALALIAPLLISCSGKKPDSNGEEYIKDTNGFDILMGQFAHNIENIWGINEVLIAGPKDYVKYSDRYLTRSHINFETGQITIETIATLDPAESLRQAIVTTLLMGDDPGAIDLYSDANDIKPSREPFLYGQVLDNTGQPIRWSGRANSFASYLLQNKLMKRTSGLHVIYSVTIQLVPNHLDKRAHKYLGMVRRASERYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVMQHTAGKDVFVSKGKWGTPSRSYLFDPEKNIDTGTAYLAILQNTYLGGIQNATSRRYAVITAYNGGAGSVLRVFSSDKGQAVSIINQMSPGDVYEALTQRHPSAESRRYLYKVNSTQKNYRRIR |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| LIPO(Sec/SPII) | 0.9992 | pos: 20-21. LIS-CS. | MAVTMKKVLALALIAPLLIS |
Protein sequence of regulator: 364 a.a. .
>REG0237 NC_013508:c294306-293215 [Edwardsiella tarda EIB202]
MAVTMKKVLALALIAPLLISCSGKKPDSNGEEYIKDTNGFDILMGQFAHNIENIWGINEVLIAGPKDYVKYSDRYLTRSH
INFETGQITIETIATLDPAESLRQAIVTTLLMGDDPGAIDLYSDANDIKPSREPFLYGQVLDNTGQPIRWSGRANSFASY
LLQNKLMKRTSGLHVIYSVTIQLVPNHLDKRAHKYLGMVRRASERYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVM
QHTAGKDVFVSKGKWGTPSRSYLFDPEKNIDTGTAYLAILQNTYLGGIQNATSRRYAVITAYNGGAGSVLRVFSSDKGQA
VSIINQMSPGDVYEALTQRHPSAESRRYLYKVNSTQKNYRRIR*
MAVTMKKVLALALIAPLLISCSGKKPDSNGEEYIKDTNGFDILMGQFAHNIENIWGINEVLIAGPKDYVKYSDRYLTRSH
INFETGQITIETIATLDPAESLRQAIVTTLLMGDDPGAIDLYSDANDIKPSREPFLYGQVLDNTGQPIRWSGRANSFASY
LLQNKLMKRTSGLHVIYSVTIQLVPNHLDKRAHKYLGMVRRASERYGVDESLILAIMQTESSFNPYAVSRSDALGLMQVM
QHTAGKDVFVSKGKWGTPSRSYLFDPEKNIDTGTAYLAILQNTYLGGIQNATSRRYAVITAYNGGAGSVLRVFSSDKGQA
VSIINQMSPGDVYEALTQRHPSAESRRYLYKVNSTQKNYRRIR*
Nucleotide sequence of regulator: 1092 bp .
>REG0237 NC_013508:c294306-293215 [Edwardsiella tarda EIB202]
ATGGCTGTTACAATGAAGAAAGTCCTTGCGCTGGCGTTAATCGCCCCGTTGTTGATCTCCTGCTCCGGCAAGAAGCCCGA
TAGCAACGGTGAAGAATATATAAAAGATACCAACGGGTTCGATATTCTCATGGGGCAGTTTGCCCACAATATTGAGAATA
TTTGGGGGATTAACGAGGTTCTGATCGCCGGGCCCAAGGACTATGTAAAATACAGCGATCGCTATCTGACCCGTAGCCAT
ATCAACTTTGAGACCGGGCAGATCACCATCGAGACCATCGCCACCCTTGACCCGGCGGAAAGCCTGCGTCAGGCCATCGT
CACCACCCTGCTGATGGGCGACGACCCCGGCGCGATCGATCTCTACTCCGATGCCAACGACATCAAGCCCAGCCGAGAGC
CCTTCCTCTACGGCCAGGTGCTGGACAACACCGGCCAGCCGATCCGCTGGTCTGGACGCGCCAACAGCTTCGCCAGCTAT
CTGCTGCAAAACAAGCTGATGAAGCGCACCTCTGGGCTGCATGTCATCTACTCCGTCACCATTCAGCTGGTACCCAACCA
TCTGGATAAGCGGGCGCACAAATATCTGGGGATGGTGCGGCGCGCCTCGGAGCGCTATGGCGTCGACGAGTCGCTGATCC
TGGCTATCATGCAGACGGAGTCCAGCTTTAACCCTTACGCCGTCAGCCGCTCCGACGCGCTGGGGCTAATGCAGGTGATG
CAGCACACCGCCGGTAAGGACGTGTTCGTCTCCAAAGGTAAGTGGGGCACCCCTAGCCGCAGCTATCTGTTTGACCCAGA
GAAAAACATCGATACCGGCACCGCCTACCTGGCTATCCTGCAGAACACCTACCTGGGGGGGATCCAGAACGCCACCTCAC
GCCGCTACGCGGTGATCACCGCCTACAACGGCGGCGCCGGCAGCGTGCTGCGCGTCTTCTCCAGCGATAAAGGGCAGGCG
GTCAGCATCATCAACCAGATGTCGCCCGGCGATGTGTATGAGGCGCTGACCCAGCGTCACCCCTCCGCCGAGTCGCGCCG
CTATCTGTATAAGGTCAACAGCACCCAGAAAAACTACCGCCGCATCCGCTAA
ATGGCTGTTACAATGAAGAAAGTCCTTGCGCTGGCGTTAATCGCCCCGTTGTTGATCTCCTGCTCCGGCAAGAAGCCCGA
TAGCAACGGTGAAGAATATATAAAAGATACCAACGGGTTCGATATTCTCATGGGGCAGTTTGCCCACAATATTGAGAATA
TTTGGGGGATTAACGAGGTTCTGATCGCCGGGCCCAAGGACTATGTAAAATACAGCGATCGCTATCTGACCCGTAGCCAT
ATCAACTTTGAGACCGGGCAGATCACCATCGAGACCATCGCCACCCTTGACCCGGCGGAAAGCCTGCGTCAGGCCATCGT
CACCACCCTGCTGATGGGCGACGACCCCGGCGCGATCGATCTCTACTCCGATGCCAACGACATCAAGCCCAGCCGAGAGC
CCTTCCTCTACGGCCAGGTGCTGGACAACACCGGCCAGCCGATCCGCTGGTCTGGACGCGCCAACAGCTTCGCCAGCTAT
CTGCTGCAAAACAAGCTGATGAAGCGCACCTCTGGGCTGCATGTCATCTACTCCGTCACCATTCAGCTGGTACCCAACCA
TCTGGATAAGCGGGCGCACAAATATCTGGGGATGGTGCGGCGCGCCTCGGAGCGCTATGGCGTCGACGAGTCGCTGATCC
TGGCTATCATGCAGACGGAGTCCAGCTTTAACCCTTACGCCGTCAGCCGCTCCGACGCGCTGGGGCTAATGCAGGTGATG
CAGCACACCGCCGGTAAGGACGTGTTCGTCTCCAAAGGTAAGTGGGGCACCCCTAGCCGCAGCTATCTGTTTGACCCAGA
GAAAAACATCGATACCGGCACCGCCTACCTGGCTATCCTGCAGAACACCTACCTGGGGGGGATCCAGAACGCCACCTCAC
GCCGCTACGCGGTGATCACCGCCTACAACGGCGGCGCCGGCAGCGTGCTGCGCGTCTTCTCCAGCGATAAAGGGCAGGCG
GTCAGCATCATCAACCAGATGTCGCCCGGCGATGTGTATGAGGCGCTGACCCAGCGTCACCCCTCCGCCGAGTCGCGCCG
CTATCTGTATAAGGTCAACAGCACCCAGAAAAACTACCGCCGCATCCGCTAA