Detailed information of regulator
Summary
Regulator ID | REG0230 |
Regulator type | protein |
Regulatory pathway (from literatures) | TCS regulatory pathway |
KEGG pathway (determined by BlastKOALA) | - |
Related T6SS | T6SS00372 (Type i4b) |
Strain | Edwardsiella tarda EIB202 |
Replicon | chromosome |
Sequence | Protein sequence (681 a.a.); Nucleotide sequence (2043 bp) |
Description | Putative activators of esrB as identified by Tn-seq. |
Reference |
External database links
Locus tag (Gene) | ETAE_1655 (prc) |
Coordinates (Strand) | 1757898..1759940 (+) |
NCBI ID | 735677771 |
RefSeq | NC_013508 |
Uniprot ID | UPI00030B4624 |
KEGG ID | - |
KEGG pathway (determined by BlastKOALA) | - |
PDB ID | - |
Target
Target | Regulation (↓/↑) | Target sequence |
---|---|---|
ETAE_0886 (esrB) promoter | ↓ | - |
Pfam domain hit(s) of regulator
Domain | Pfam ID | E-value | Aligned region |
---|---|---|---|
TSP_NTD | PF17804.3 | 4.1e-58 | 49..232 |
Peptidase_S41 | PF03572.20 | 1.9e-52 | 357..530 |
DUF3340 | PF11818.10 | 8.1e-39 | 535..667 |
PDZ | PF00595.26 | 2.8e-14 | 242..321 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
Prediction | Region | Sequence |
---|---|---|
Outside | 1-680 | MNNFFRVSAIALSLFAGTVFAADDAVSGAVQLPQLHQEPQHATVSERVTARFTRSHYRQFDLNADFSKKIFNRYLNMLDYNHNVFLASDIARFRDREGKLGDELRSGQLDTAYALFNLSQQRRLERYEYALTLLKKPMSFDGSDTIDVDRSKAPWPTSVAELDKLWYAKVKYDALNLKLAGKDWPEIQKILTKRYQFAIKRLTQGNSEDVFQLFMNAFAREIDPHTSYLSPRNTEQFNTDMSLSLEGIGAVLQQTEDDYTQINSLVAGGPAAKSKVLKVGDRIVAVGQPGKAMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRIVTLTRERIRLEDRAVKMSVKTVDGHKIGVLDIPGFYVGLTEDVKVQLQKLEKQHVSAIVIDLRGNGGGALTEAVSLSGLFIPSGPVVQVRDNVGKVREDDDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYDRALIVGEPTFGKGTVQQYRSVNRIYDQMLRPEWPDLGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGIDPADTGESFEDNALPWDSINAAAYNKAGDVQRFDPQLIVLHDARIAKDPEFQYIEQDIAHYKALKARRNIVSLNYAQREKENKDDDAIRLQRINARLKLEGKKPIASLDDIPKDYQEPDPYLNETVKIAEDLALLEQKNAQQAQE |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction | Probability | Cleavage site | Signal peptide sequence |
---|---|---|---|
SP(Sec/SPI) | 0.9969 | pos: 21-22. VFA-AD. | MNNFFRVSAIALSLFAGTVFA |
Protein sequence of regulator: 681 a.a. .
>REG0230 NC_013508:1757898-1759940 [Edwardsiella tarda EIB202]
MNNFFRVSAIALSLFAGTVFAADDAVSGAVQLPQLHQEPQHATVSERVTARFTRSHYRQFDLNADFSKKIFNRYLNMLDY
NHNVFLASDIARFRDREGKLGDELRSGQLDTAYALFNLSQQRRLERYEYALTLLKKPMSFDGSDTIDVDRSKAPWPTSVA
ELDKLWYAKVKYDALNLKLAGKDWPEIQKILTKRYQFAIKRLTQGNSEDVFQLFMNAFAREIDPHTSYLSPRNTEQFNTD
MSLSLEGIGAVLQQTEDDYTQINSLVAGGPAAKSKVLKVGDRIVAVGQPGKAMVDVIGWRLDDVVALIKGPKGSKVRLEI
LPAGKGTKTRIVTLTRERIRLEDRAVKMSVKTVDGHKIGVLDIPGFYVGLTEDVKVQLQKLEKQHVSAIVIDLRGNGGGA
LTEAVSLSGLFIPSGPVVQVRDNVGKVREDDDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYDRALIVGEPTFGKGT
VQQYRSVNRIYDQMLRPEWPDLGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGIDPADTGESFEDNALPWDSINAAAYN
KAGDVQRFDPQLIVLHDARIAKDPEFQYIEQDIAHYKALKARRNIVSLNYAQREKENKDDDAIRLQRINARLKLEGKKPI
ASLDDIPKDYQEPDPYLNETVKIAEDLALLEQKNAQQAQE*
MNNFFRVSAIALSLFAGTVFAADDAVSGAVQLPQLHQEPQHATVSERVTARFTRSHYRQFDLNADFSKKIFNRYLNMLDY
NHNVFLASDIARFRDREGKLGDELRSGQLDTAYALFNLSQQRRLERYEYALTLLKKPMSFDGSDTIDVDRSKAPWPTSVA
ELDKLWYAKVKYDALNLKLAGKDWPEIQKILTKRYQFAIKRLTQGNSEDVFQLFMNAFAREIDPHTSYLSPRNTEQFNTD
MSLSLEGIGAVLQQTEDDYTQINSLVAGGPAAKSKVLKVGDRIVAVGQPGKAMVDVIGWRLDDVVALIKGPKGSKVRLEI
LPAGKGTKTRIVTLTRERIRLEDRAVKMSVKTVDGHKIGVLDIPGFYVGLTEDVKVQLQKLEKQHVSAIVIDLRGNGGGA
LTEAVSLSGLFIPSGPVVQVRDNVGKVREDDDTDGVVYYKGPLVVLVDRFSASASEIFAAAMQDYDRALIVGEPTFGKGT
VQQYRSVNRIYDQMLRPEWPDLGSVQYTIQKFYRINGGSTQRKGVTPDIVMPTGIDPADTGESFEDNALPWDSINAAAYN
KAGDVQRFDPQLIVLHDARIAKDPEFQYIEQDIAHYKALKARRNIVSLNYAQREKENKDDDAIRLQRINARLKLEGKKPI
ASLDDIPKDYQEPDPYLNETVKIAEDLALLEQKNAQQAQE*
Nucleotide sequence of regulator: 2043 bp .
>REG0230 NC_013508:1757898-1759940 [Edwardsiella tarda EIB202]
ATGAACAATTTTTTCCGGGTATCGGCAATCGCCCTGTCGCTGTTTGCAGGTACCGTTTTTGCAGCGGATGACGCCGTCAG
CGGCGCCGTCCAGCTGCCCCAGTTGCATCAGGAACCTCAGCATGCAACGGTCAGTGAACGTGTGACCGCACGTTTCACCC
GCTCCCATTACCGCCAGTTTGACCTCAACGCAGACTTCTCGAAGAAAATCTTCAACCGCTACCTGAACATGCTGGACTAT
AACCACAACGTGTTTCTGGCATCGGATATCGCCCGCTTCCGCGATCGCGAAGGCAAGCTGGGCGATGAGCTGCGCAGCGG
TCAGCTGGATACGGCCTATGCGCTGTTTAACCTGTCTCAGCAGCGCCGCCTGGAGCGTTATGAGTACGCCCTGACGCTGC
TGAAAAAGCCGATGAGCTTTGACGGCAGCGACACCATCGACGTCGATCGCAGCAAGGCGCCGTGGCCGACCAGCGTCGCC
GAGCTGGACAAGCTCTGGTACGCCAAGGTGAAGTATGACGCACTGAACCTGAAGCTGGCCGGTAAGGACTGGCCGGAGAT
CCAGAAGATCCTGACCAAACGCTATCAGTTCGCCATTAAGCGCCTGACCCAGGGCAACAGCGAGGATGTCTTCCAGCTGT
TTATGAATGCGTTTGCCCGAGAGATCGATCCCCATACCAGCTACCTGTCGCCGCGCAATACCGAGCAGTTCAATACGGAC
ATGAGTCTGTCGCTGGAGGGCATCGGCGCGGTGCTGCAGCAGACAGAGGATGACTACACCCAGATTAACTCTCTGGTGGC
CGGCGGTCCGGCGGCCAAGAGCAAGGTGCTGAAGGTGGGCGATCGCATCGTGGCGGTCGGCCAGCCGGGTAAGGCGATGG
TCGATGTGATCGGCTGGCGTCTGGACGACGTGGTCGCCCTGATCAAAGGGCCGAAGGGCAGCAAGGTGCGCCTGGAGATC
CTGCCGGCGGGTAAAGGAACCAAAACCCGTATCGTCACCCTGACCCGCGAACGTATCCGCCTGGAAGATCGCGCCGTGAA
GATGAGTGTCAAAACGGTGGATGGCCATAAAATCGGCGTGTTGGATATTCCCGGCTTCTACGTCGGCCTGACGGAGGACG
TCAAGGTTCAGCTGCAGAAGCTGGAGAAACAGCACGTGAGCGCCATCGTCATCGATCTGCGCGGCAACGGGGGCGGTGCC
CTGACAGAGGCCGTGTCCCTGTCGGGTCTGTTTATTCCCAGCGGGCCGGTGGTGCAGGTGCGCGATAACGTCGGCAAGGT
GCGTGAGGATGACGATACCGACGGCGTTGTCTACTACAAAGGACCGCTGGTGGTGCTGGTCGATCGCTTTAGCGCCTCGG
CATCCGAGATTTTCGCCGCCGCCATGCAGGACTACGATCGCGCCCTGATCGTGGGTGAACCCACCTTCGGCAAGGGAACG
GTACAGCAGTACCGCTCAGTGAACCGCATTTACGATCAGATGCTGCGTCCAGAGTGGCCGGATCTGGGTTCGGTGCAGTA
CACCATCCAGAAGTTTTACCGCATCAACGGCGGCAGCACCCAGCGCAAAGGGGTGACGCCGGACATCGTGATGCCGACCG
GTATCGATCCGGCGGACACCGGCGAGAGCTTTGAGGATAACGCGCTGCCGTGGGATAGCATCAACGCCGCCGCCTATAAT
AAGGCTGGCGATGTACAGCGCTTTGATCCGCAGCTGATCGTGCTACACGATGCGCGCATCGCCAAAGATCCCGAGTTCCA
GTACATCGAACAGGATATTGCCCACTACAAGGCGCTCAAGGCGCGCCGTAACATTGTCTCTCTGAACTACGCTCAGCGTG
AAAAGGAGAACAAGGACGACGACGCGATTCGCCTGCAGCGGATCAACGCCCGGCTGAAGCTGGAGGGCAAGAAGCCGATC
GCCTCGCTGGATGATATTCCTAAGGATTATCAGGAGCCGGATCCCTACCTGAATGAGACGGTGAAAATCGCCGAAGATCT
GGCCCTGCTGGAGCAGAAAAACGCACAGCAGGCTCAGGAGTAG
ATGAACAATTTTTTCCGGGTATCGGCAATCGCCCTGTCGCTGTTTGCAGGTACCGTTTTTGCAGCGGATGACGCCGTCAG
CGGCGCCGTCCAGCTGCCCCAGTTGCATCAGGAACCTCAGCATGCAACGGTCAGTGAACGTGTGACCGCACGTTTCACCC
GCTCCCATTACCGCCAGTTTGACCTCAACGCAGACTTCTCGAAGAAAATCTTCAACCGCTACCTGAACATGCTGGACTAT
AACCACAACGTGTTTCTGGCATCGGATATCGCCCGCTTCCGCGATCGCGAAGGCAAGCTGGGCGATGAGCTGCGCAGCGG
TCAGCTGGATACGGCCTATGCGCTGTTTAACCTGTCTCAGCAGCGCCGCCTGGAGCGTTATGAGTACGCCCTGACGCTGC
TGAAAAAGCCGATGAGCTTTGACGGCAGCGACACCATCGACGTCGATCGCAGCAAGGCGCCGTGGCCGACCAGCGTCGCC
GAGCTGGACAAGCTCTGGTACGCCAAGGTGAAGTATGACGCACTGAACCTGAAGCTGGCCGGTAAGGACTGGCCGGAGAT
CCAGAAGATCCTGACCAAACGCTATCAGTTCGCCATTAAGCGCCTGACCCAGGGCAACAGCGAGGATGTCTTCCAGCTGT
TTATGAATGCGTTTGCCCGAGAGATCGATCCCCATACCAGCTACCTGTCGCCGCGCAATACCGAGCAGTTCAATACGGAC
ATGAGTCTGTCGCTGGAGGGCATCGGCGCGGTGCTGCAGCAGACAGAGGATGACTACACCCAGATTAACTCTCTGGTGGC
CGGCGGTCCGGCGGCCAAGAGCAAGGTGCTGAAGGTGGGCGATCGCATCGTGGCGGTCGGCCAGCCGGGTAAGGCGATGG
TCGATGTGATCGGCTGGCGTCTGGACGACGTGGTCGCCCTGATCAAAGGGCCGAAGGGCAGCAAGGTGCGCCTGGAGATC
CTGCCGGCGGGTAAAGGAACCAAAACCCGTATCGTCACCCTGACCCGCGAACGTATCCGCCTGGAAGATCGCGCCGTGAA
GATGAGTGTCAAAACGGTGGATGGCCATAAAATCGGCGTGTTGGATATTCCCGGCTTCTACGTCGGCCTGACGGAGGACG
TCAAGGTTCAGCTGCAGAAGCTGGAGAAACAGCACGTGAGCGCCATCGTCATCGATCTGCGCGGCAACGGGGGCGGTGCC
CTGACAGAGGCCGTGTCCCTGTCGGGTCTGTTTATTCCCAGCGGGCCGGTGGTGCAGGTGCGCGATAACGTCGGCAAGGT
GCGTGAGGATGACGATACCGACGGCGTTGTCTACTACAAAGGACCGCTGGTGGTGCTGGTCGATCGCTTTAGCGCCTCGG
CATCCGAGATTTTCGCCGCCGCCATGCAGGACTACGATCGCGCCCTGATCGTGGGTGAACCCACCTTCGGCAAGGGAACG
GTACAGCAGTACCGCTCAGTGAACCGCATTTACGATCAGATGCTGCGTCCAGAGTGGCCGGATCTGGGTTCGGTGCAGTA
CACCATCCAGAAGTTTTACCGCATCAACGGCGGCAGCACCCAGCGCAAAGGGGTGACGCCGGACATCGTGATGCCGACCG
GTATCGATCCGGCGGACACCGGCGAGAGCTTTGAGGATAACGCGCTGCCGTGGGATAGCATCAACGCCGCCGCCTATAAT
AAGGCTGGCGATGTACAGCGCTTTGATCCGCAGCTGATCGTGCTACACGATGCGCGCATCGCCAAAGATCCCGAGTTCCA
GTACATCGAACAGGATATTGCCCACTACAAGGCGCTCAAGGCGCGCCGTAACATTGTCTCTCTGAACTACGCTCAGCGTG
AAAAGGAGAACAAGGACGACGACGCGATTCGCCTGCAGCGGATCAACGCCCGGCTGAAGCTGGAGGGCAAGAAGCCGATC
GCCTCGCTGGATGATATTCCTAAGGATTATCAGGAGCCGGATCCCTACCTGAATGAGACGGTGAAAATCGCCGAAGATCT
GGCCCTGCTGGAGCAGAAAAACGCACAGCAGGCTCAGGAGTAG