Detailed information of regulator

Summary

Regulator ID	REG0222
Regulator type	protein
Regulatory pathway (from literatures)	TCS regulatory pathway
KEGG pathway (determined by BlastKOALA)	-
Related T6SS	T6SS00372 (Type i4b)
Strain	Edwardsiella tarda EIB202
Replicon	chromosome
Sequence	Protein sequence (227 a.a.); Nucleotide sequence (681 bp)
Description	Putative repressors of esrB as identified by Tn-seq.
Reference	[1] Yin K, Guan Y, Ma R, et al. Critical role for a promoter discriminator in RpoS control of virulence in Edwardsiella piscicida. PLoS Pathog. 2018 Aug 31;14(8):e1007272. doi: 10.1371/journal.ppat.1007272. eCollection 2018 Aug. PMID: 30169545

---

External database links

Locus tag (Gene)	ETAE_0430
Coordinates (Strand)	473075..473755 (-)
NCBI ID	502610291
RefSeq	NC_013508
Uniprot ID	A0A034T1Q2_9GAMM, D0ZB99_EDWTE, A0A076LSR0_9GAMM, A0A0H3DMH0_EDWTF
KEGG ID	etr:ETAE_0430, etd:ETAF_0384, ete:ETEE_2190
KEGG pathway (determined by BlastKOALA)	-
PDB ID	-

---

  Target

Target	Regulation (↓/↑)	Target sequence
ETAE_0886 (esrB) promoter	↑	-

---

Pfam domain hit(s) of regulator

Domain	Pfam ID	E-value	Aligned region
SNARE_assoc	PF09335.13	4.2e-24	48..173

---

Transmembrane helices

• Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Inside	1-18	MDIIRELITALWHQDYET
Transmembrane helix	19-38	LANPSLVWTIYGILFVILFL
Outside	39-41	ENG
Transmembrane helix	42-61	LLPAAFLPGDSLLILVGVLI
Inside	62-67	ARDTMD
Transmembrane helix	68-90	FPLTLLVLTSAASLGCWVGYLQG
Outside	91-125	RWLGNTHLVQKWLSHLPAHYHQRAHQLFHRHGLAA
Transmembrane helix	126-148	LLIGRFLAFVRTLLPLIAGLSGL
Inside	149-154	NGPRFQ
Transmembrane helix	155-175	FFNWISGLLWVLILSSLGYVL
Outside	176-189	GKTPLFLRYEDQLM
Transmembrane helix	190-212	NLLMLLPLVLLVFGLCGSLLVLW
Inside	213-226	RKKHAHATGKSPRK

---

Signal peptides

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9987	-	-

---

  Protein sequence of regulator: 227 a.a.    .Download


  Nucleotide sequence of regulator: 681 bp    .Download