Detailed information of regulator
Summary
| Regulator ID | REG0221  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | TCS regulatory pathway |
| KEGG pathway (determined by BlastKOALA) | - |
| Related T6SS | T6SS00372 (Type i4b) |
| Strain | Edwardsiella tarda EIB202 |
| Replicon | chromosome |
| Sequence | Protein sequence (162 a.a.); Nucleotide sequence (486 bp) |
| Description | Putative repressors of esrB as identified by Tn-seq. |
| Reference |
External database links
| Locus tag (Gene) | ETAE_1412 |
| Coordinates (Strand) | 1522924..1523409 (-) |
| NCBI ID | 502611274 |
| RefSeq | NC_013508 |
| Uniprot ID | D0ZGX7_EDWTE, A0A0H3DPV0_EDWTF |
| KEGG ID | etr:ETAE_1412, etd:ETAF_1308 |
| KEGG pathway (determined by BlastKOALA) | - |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| ETAE_0886 (esrB) promoter | ↑ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| Haem_degrading | PF03928.16 | 2.2e-32 | 22..149 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-161 | MSSEEALARLAAEEQQLQFTLFNPDTAWQLGCALRQEAERRGLHVTIDIQFADQTLFHCAMPGTSPDNAEWIRRKRNVVLRFQRSSYAMGMRLTLRNTTLEAFYGLSPADYAPQGGSFPLRIANCGCVGAISVSGAPQLDDHLLVSEVIARFLGINQQNHA |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9827 | - | - |
Protein sequence of regulator: 162 a.a. .
>REG0221 NC_013508:c1523409-1522924 [Edwardsiella tarda EIB202]
MSSEEALARLAAEEQQLQFTLFNPDTAWQLGCALRQEAERRGLHVTIDIQFADQTLFHCAMPGTSPDNAEWIRRKRNVVL
RFQRSSYAMGMRLTLRNTTLEAFYGLSPADYAPQGGSFPLRIANCGCVGAISVSGAPQLDDHLLVSEVIARFLGINQQNH
A*
MSSEEALARLAAEEQQLQFTLFNPDTAWQLGCALRQEAERRGLHVTIDIQFADQTLFHCAMPGTSPDNAEWIRRKRNVVL
RFQRSSYAMGMRLTLRNTTLEAFYGLSPADYAPQGGSFPLRIANCGCVGAISVSGAPQLDDHLLVSEVIARFLGINQQNH
A*
Nucleotide sequence of regulator: 486 bp .
>REG0221 NC_013508:c1523409-1522924 [Edwardsiella tarda EIB202]
ATGAGCAGTGAAGAAGCGCTGGCGCGACTGGCCGCCGAGGAGCAGCAGCTCCAGTTTACCCTATTCAACCCCGATACCGC
CTGGCAGCTAGGCTGTGCGCTGCGTCAGGAGGCCGAGCGGCGCGGCCTGCACGTCACCATCGATATCCAGTTCGCCGATC
AAACCCTATTTCACTGCGCCATGCCCGGCACCTCGCCGGACAACGCCGAATGGATCCGCCGCAAGCGCAACGTCGTACTG
CGCTTCCAGCGCAGCTCCTATGCGATGGGGATGCGCTTGACCCTGCGAAATACCACGCTAGAGGCCTTTTACGGCCTGAG
CCCGGCCGACTATGCCCCCCAGGGCGGCAGCTTCCCGCTGCGTATCGCCAACTGCGGCTGCGTCGGCGCCATCAGCGTGT
CCGGCGCCCCCCAGCTGGACGACCATCTGTTGGTCAGCGAGGTTATTGCCCGCTTTCTTGGCATTAACCAACAAAACCAT
GCCTAA
ATGAGCAGTGAAGAAGCGCTGGCGCGACTGGCCGCCGAGGAGCAGCAGCTCCAGTTTACCCTATTCAACCCCGATACCGC
CTGGCAGCTAGGCTGTGCGCTGCGTCAGGAGGCCGAGCGGCGCGGCCTGCACGTCACCATCGATATCCAGTTCGCCGATC
AAACCCTATTTCACTGCGCCATGCCCGGCACCTCGCCGGACAACGCCGAATGGATCCGCCGCAAGCGCAACGTCGTACTG
CGCTTCCAGCGCAGCTCCTATGCGATGGGGATGCGCTTGACCCTGCGAAATACCACGCTAGAGGCCTTTTACGGCCTGAG
CCCGGCCGACTATGCCCCCCAGGGCGGCAGCTTCCCGCTGCGTATCGCCAACTGCGGCTGCGTCGGCGCCATCAGCGTGT
CCGGCGCCCCCCAGCTGGACGACCATCTGTTGGTCAGCGAGGTTATTGCCCGCTTTCTTGGCATTAACCAACAAAACCAT
GCCTAA