Detailed information of regulator


Summary

Regulator ID REG0241 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) beta-Lactam resistance (map01501); Cationic antimicrobial peptide (CAMP) resistance (map01503)
Related T6SS T6SS00372 experimental (Type i4b)
Strain Edwardsiella tarda EIB202
Replicon chromosome
Sequence Protein sequence (1051 a.a.); Nucleotide sequence (3153 bp)
Description Putative activators of esrB as identified by Tn-seq.
Reference
External database links

Locus tag (Gene) ETAE_1010 (acrB)
Coordinates (Strand) 1099309..1102461 (-)
NCBI ID 502610875
RefSeq NC_013508
Uniprot ID D0ZEC4_EDWTE, A0A0H3DR69_EDWTF
KEGG ID etd:ETAF_0941, etr:ETAE_1010
KEGG pathway (determined by BlastKOALA) map01501; map01503
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
ETAE_0886 (esrB) promoter ↓ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
ACR_tran PF00873.21 0 1..1029
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-9 MAKFFIDRP
Transmembrane helix 10-32 IFAWVLAIIMMLAGALAIMSLPV
Inside 33-339 AQYPTVAPPAVTISASYPGADAATVQNSVTQVIEQNMNGIDNLMYMSSTSDSAGNASITLTFEAGTDPDIAQVQVQNKLQLAMPSLPQEVQQQGVSVDKASSSILLVAGFISEDGSLSQDDIADYVASNIKDPLSRTQGVGSVQLFGSQYAMRIWLDPNKLNKYNLTPVDVVSQIKVQNNQIAGGQLGGTPPVPGQQLNASIIVQTRLKDPTEFGKILLKVQQDGSRVLLRDVARVELGAENYGTIARYNGKPAAGIAVKLATGANALDTAKAVKTELAKLAPYFPASLKTVYPYDTTPFVQLSIDE
Transmembrane helix 340-362 VVKTLLEAIVLVFVVMYLFLQNI
Outside 363-365 RAT
Transmembrane helix 366-388 LIPTIAVPVVLLGTFAILEIVGF
Inside 389-437 SINTLTMFGMVLAIGLLVDDAIVVVENVERVMSEEGLPPKEATKKSMEQ
Transmembrane helix 438-460 IQGALVGIAMVLSAVFVPMAFFG
Outside 461-469 GSTGAIYRQ
Transmembrane helix 470-492 FSITIVSSMVLSVLVAMILTPAL
Inside 493-540 CATMLKPIAKGDHGVQTGFFGWFNRLFEKSTHHYTDSVGRILRGTGRY
Transmembrane helix 541-563 LVIYLLIVVGMGLLFIRLPTSFL
Outside 564-871 PEEDQGVLLTMAQLPPGATQERTNNVLKQVSQYYLTKEKDNVESVFTVSGFGFSGQGQNNGLAFVSLKPWDERKGDQNKVTAIIQRAAGAFSKINDAMVYPFNLPAIVELGTASGFDFELIDQANLGHEKLTEARNQLLGMAAQHPDLLVGVRPNGLEDTPQFKLDIDQEKAQSLGVSLADVNQTISAALGGAYVNDFIDRGRVKRVYVQADAPFRMLPSDIDNWYVRSSNGQMVPLSAFSSSRWEYGSPRLERYNGLPSMEILGEAAPGKSTGEAMALMESLVAKLPAGVGYDWTGMSYQERLSGNQ
Transmembrane helix 872-891 APALYAISLIVVFLCLAALY
Inside 892-897 ESWSIP
Transmembrane helix 898-920 FSVMLVVPLGVVGALLATSLRGL
Outside 921-924 TNDV
Transmembrane helix 925-947 YFQVGLLTTIGLSAKNAILIVEF
Inside 948-973 AVDLMHKEGKGLVEATLEAVRMRLRP
Transmembrane helix 974-996 ILMTSLAFILGVMPLVISNGAGS
Outside 997-1005 GAQNAVGTG
Transmembrane helix 1006-1028 VMGGMVSATILAIFFVPVFFVVV
Inside 1029-1050 RRRFGRRGEDIEHNHPVEPHNK


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.6383 - -


  Protein sequence of regulator: 1051 a.a.    .

>REG0241 NC_013508:c1102461-1099309 [Edwardsiella tarda EIB202]
MAKFFIDRPIFAWVLAIIMMLAGALAIMSLPVAQYPTVAPPAVTISASYPGADAATVQNSVTQVIEQNMNGIDNLMYMSS
TSDSAGNASITLTFEAGTDPDIAQVQVQNKLQLAMPSLPQEVQQQGVSVDKASSSILLVAGFISEDGSLSQDDIADYVAS
NIKDPLSRTQGVGSVQLFGSQYAMRIWLDPNKLNKYNLTPVDVVSQIKVQNNQIAGGQLGGTPPVPGQQLNASIIVQTRL
KDPTEFGKILLKVQQDGSRVLLRDVARVELGAENYGTIARYNGKPAAGIAVKLATGANALDTAKAVKTELAKLAPYFPAS
LKTVYPYDTTPFVQLSIDEVVKTLLEAIVLVFVVMYLFLQNIRATLIPTIAVPVVLLGTFAILEIVGFSINTLTMFGMVL
AIGLLVDDAIVVVENVERVMSEEGLPPKEATKKSMEQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSSMVL
SVLVAMILTPALCATMLKPIAKGDHGVQTGFFGWFNRLFEKSTHHYTDSVGRILRGTGRYLVIYLLIVVGMGLLFIRLPT
SFLPEEDQGVLLTMAQLPPGATQERTNNVLKQVSQYYLTKEKDNVESVFTVSGFGFSGQGQNNGLAFVSLKPWDERKGDQ
NKVTAIIQRAAGAFSKINDAMVYPFNLPAIVELGTASGFDFELIDQANLGHEKLTEARNQLLGMAAQHPDLLVGVRPNGL
EDTPQFKLDIDQEKAQSLGVSLADVNQTISAALGGAYVNDFIDRGRVKRVYVQADAPFRMLPSDIDNWYVRSSNGQMVPL
SAFSSSRWEYGSPRLERYNGLPSMEILGEAAPGKSTGEAMALMESLVAKLPAGVGYDWTGMSYQERLSGNQAPALYAISL
IVVFLCLAALYESWSIPFSVMLVVPLGVVGALLATSLRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAVDLMHKEGKGLV
EATLEAVRMRLRPILMTSLAFILGVMPLVISNGAGSGAQNAVGTGVMGGMVSATILAIFFVPVFFVVVRRRFGRRGEDIE
HNHPVEPHNK*

  Nucleotide sequence of regulator: 3153 bp    .

>REG0241 NC_013508:c1102461-1099309 [Edwardsiella tarda EIB202]
ATGGCTAAGTTTTTTATCGATCGTCCGATCTTTGCCTGGGTTCTCGCCATCATCATGATGTTGGCCGGTGCATTGGCGAT
CATGAGTCTGCCGGTCGCACAGTACCCTACCGTTGCGCCGCCGGCAGTCACCATCTCCGCCAGCTATCCGGGGGCGGATG
CGGCCACGGTGCAAAACTCCGTGACGCAGGTTATCGAACAGAACATGAACGGTATCGATAACCTGATGTACATGTCGTCA
ACCAGTGACTCGGCCGGTAACGCCAGCATCACCCTGACCTTCGAGGCCGGTACCGATCCGGATATCGCTCAGGTCCAGGT
GCAGAACAAGCTACAGCTGGCCATGCCCTCCCTGCCGCAGGAAGTACAGCAGCAGGGCGTCAGCGTGGATAAGGCCTCCA
GCAGTATTCTGCTGGTCGCAGGCTTTATCTCCGAAGACGGCAGCCTGAGTCAGGATGACATCGCCGACTATGTGGCGTCC
AACATTAAGGATCCCCTGAGCCGTACCCAGGGCGTCGGCAGCGTACAGCTGTTCGGCTCCCAGTACGCCATGCGTATCTG
GCTGGACCCCAACAAGCTGAATAAGTACAACCTGACGCCGGTCGACGTGGTCTCCCAGATTAAGGTGCAGAACAACCAGA
TCGCCGGTGGCCAGCTGGGGGGAACCCCGCCGGTGCCGGGACAGCAGCTGAACGCCTCGATCATCGTGCAGACCCGTCTG
AAGGATCCGACCGAGTTCGGCAAGATTCTGCTTAAGGTCCAACAGGATGGTTCCCGCGTTCTGCTGCGCGACGTTGCGCG
CGTAGAGCTGGGGGCGGAAAACTATGGCACCATCGCCCGCTATAACGGTAAACCGGCCGCCGGTATCGCCGTGAAGCTCG
CGACCGGCGCCAACGCGCTGGACACCGCCAAGGCCGTGAAGACGGAGCTGGCCAAGCTGGCCCCTTACTTCCCGGCAAGC
CTGAAGACGGTCTACCCGTATGACACCACGCCGTTCGTTCAGCTCTCGATCGACGAAGTGGTGAAGACCCTGCTGGAAGC
GATCGTGCTGGTGTTCGTGGTGATGTATCTGTTCCTGCAGAATATCCGCGCTACCCTGATCCCCACCATCGCCGTACCGG
TGGTACTGCTGGGGACCTTCGCTATCCTGGAGATCGTGGGCTTCTCCATCAACACCCTGACCATGTTCGGGATGGTGTTG
GCGATAGGCCTCTTGGTGGATGACGCCATCGTGGTGGTGGAGAACGTCGAGCGCGTCATGTCCGAAGAGGGGCTGCCACC
GAAAGAGGCGACCAAGAAGTCCATGGAGCAGATCCAGGGGGCGCTGGTCGGTATCGCCATGGTGCTCTCCGCGGTCTTCG
TACCGATGGCCTTCTTCGGCGGCTCAACCGGGGCCATCTATCGCCAGTTCTCCATCACCATCGTCTCCTCCATGGTGCTG
TCAGTGCTGGTGGCGATGATCCTGACGCCGGCGCTGTGTGCGACTATGCTCAAACCGATCGCCAAAGGCGATCACGGCGT
ACAGACCGGCTTCTTTGGCTGGTTTAACCGCCTGTTTGAAAAGAGCACTCACCACTATACCGACAGCGTTGGCCGCATCC
TGCGCGGCACCGGGCGCTATCTGGTGATTTACCTGCTGATCGTAGTCGGCATGGGGCTGCTGTTTATCCGCCTGCCCACC
TCCTTCCTGCCGGAAGAGGACCAGGGGGTACTGCTGACCATGGCCCAGCTGCCGCCGGGCGCGACCCAGGAGCGCACCAA
CAATGTGCTCAAGCAGGTCTCCCAGTACTACCTGACCAAAGAAAAAGATAACGTTGAATCGGTCTTTACCGTCAGCGGCT
TCGGCTTCAGCGGTCAGGGGCAGAACAACGGTCTGGCCTTCGTCAGTCTGAAGCCATGGGACGAGCGTAAGGGCGATCAG
AACAAGGTTACCGCGATCATTCAACGTGCGGCGGGCGCCTTCAGTAAGATCAACGACGCCATGGTGTATCCGTTTAACCT
GCCGGCTATCGTTGAGCTGGGTACGGCATCCGGCTTCGACTTTGAGCTTATCGATCAGGCCAACCTGGGCCACGAAAAGC
TGACCGAAGCGCGTAACCAGCTGCTGGGCATGGCGGCGCAGCACCCTGACCTGCTGGTCGGCGTGCGCCCCAACGGCCTG
GAAGATACGCCGCAGTTCAAGCTGGATATCGACCAAGAAAAAGCGCAGTCGCTGGGGGTTTCTCTCGCCGACGTTAACCA
GACTATCTCTGCCGCGCTGGGCGGGGCCTACGTCAACGACTTTATCGACCGCGGACGCGTCAAACGCGTTTATGTCCAGG
CCGATGCGCCGTTCCGTATGCTGCCAAGCGATATCGATAACTGGTACGTGCGCAGCAGCAATGGTCAGATGGTACCGCTG
TCCGCCTTTTCCAGCTCACGCTGGGAGTACGGCTCACCGCGTCTGGAGCGCTACAACGGTCTGCCCTCCATGGAGATCCT
GGGCGAAGCCGCACCCGGTAAGAGTACCGGTGAGGCCATGGCGCTGATGGAGTCCCTGGTCGCCAAGCTGCCGGCGGGCG
TCGGTTATGACTGGACCGGTATGTCCTATCAGGAACGCCTGTCCGGCAACCAGGCTCCGGCCCTGTATGCCATCTCGCTG
ATCGTGGTCTTCCTGTGTCTGGCCGCCCTGTATGAGAGCTGGTCTATTCCGTTCTCCGTCATGCTGGTGGTCCCGCTCGG
CGTCGTCGGCGCCCTGTTGGCGACCTCGCTGCGCGGCCTGACCAACGACGTGTACTTCCAGGTCGGCCTGTTGACGACGA
TCGGGCTATCGGCGAAGAACGCCATCCTGATCGTCGAATTCGCCGTCGACCTGATGCACAAAGAGGGTAAGGGGCTGGTA
GAAGCGACGCTGGAGGCGGTGCGTATGCGTCTGCGCCCGATCCTGATGACCTCGCTGGCCTTTATTCTCGGGGTTATGCC
GCTGGTCATCAGCAACGGCGCGGGCTCCGGAGCCCAGAACGCCGTCGGTACCGGGGTCATGGGCGGGATGGTCTCCGCTA
CCATTCTGGCCATCTTCTTCGTACCGGTGTTCTTTGTGGTGGTGCGCCGCCGCTTTGGCCGCCGCGGCGAGGATATTGAG
CACAACCATCCGGTTGAACCGCACAATAAATAG