Detailed information of T6SS
Note: only experimentally validated proteins are displayed in the graph.
Summary
| T6SS ID | T6SS00346  |
| T6SS type | Type i4b |
| Strain | Edwardsiella ictaluri 93-146 |
| Replicon (RefSeq) | chromosome (NC_012779) |
| Location | 2631752..2651730 |
| Function | effector translocation; virulence |
| Comment | - |
| References | [1] Rogge ML et al (2011) Regulation of the Edwardsiella ictaluri type III secretion system by pH and phosphate concentration through EsrA, EsrB, and EsrC. Appl Environ Microbiol. 77(13):4293-302. [PudMed:21551284] |
Experimental investigation has been performed.T6SS components and genome coordinates
| Component | PAAR | TssA | TssB | TssC | TssD | TssE | TssF | TssG | TssH | TssI | TssJ | TssK | TssL | TssM |
| Number | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
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Component ID | Component | Locus tag (Gene) | Coordinate | Strand | Size (bp) | NCBI ID | Product |
|---|---|---|---|---|---|---|---|
| NT01EI_RS11875 | 2627131..2628156 | + | 1026 | WP_015870885.1 | IS110 family transposase | ||
| NT01EI_RS18465 | 2628438..2628935 | - | 498 | pseudogene | IS5 family transposase | ||
| NT01EI_RS11880 | 2628968..2630176 | - | 1209 | WP_015870371.1 | IS256-like element ISEic2 family transposase | ||
| NT01EI_RS11885 | 2630250..2630561 | - | 312 | pseudogene | IS5 family transposase | ||
| NT01EI_RS20225 | 2631188..2631489 | + | 302 | pseudogene | type VI secretion protein | ||
| T6CP008364 | TssB | NT01EI_RS11890 (tssB) | 2631739..2632251 | + | 513 | WP_015872006.1 | type VI secretion system contractile sheath small subunit |
| T6CP008365 | TssC | NT01EI_RS11895 (tssC) | 2632251..2633738 | + | 1488 | WP_015872007.1 | type VI secretion system contractile sheath large subunit |
| T6CP009343 | TssD | NT01EI_RS11900 | 2633808..2634299 | + | 492 | WP_015872008.1 | type VI secretion system tube protein Hcp |
| NT01EI_RS11905 | 2634429..2635640 | + | 1212 | WP_015872009.1 | hypothetical protein | ||
| T6CP008366 | TssE | NT01EI_RS11910 (tssE) | 2635649..2636125 | + | 477 | WP_015872010.1 | type VI secretion system baseplate subunit TssE |
Genes in the 5-Kb flanking regions if available, or non-core components encoded by the T6SS gene cluster if any.
Download FASTA format files
Note: in the 'Target' column, ↓ means the target is positively regulated by the regulator, while ↑ indicates negatively regulation.
Experimental investigation has been performed.
Bioinformatics investigation has been performed.
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Regulator ID | Locus tag (Gene) | Regulator type | Regulatory pathway | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Target (Regulation) |
|---|---|---|---|---|---|---|---|---|
| REG0204 | NT01EI_RS04325 (EsrB) | protein | TCS-RR | Edwardsiella ictaluri 93-146 | chromosome (NC_012779) | 955101..955745 (-) | 506350644 | T6SS translocon protein EvpC secretion (↓) |
| REG0205 | NT01EI_RS04200 (EsrC) | protein | TCS regulatory pathway | Edwardsiella ictaluri 93-146 | chromosome (NC_012779) | 933326..934018 (-) | 737638726 | T6SS translocon protein EvpC secretion (↓) |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Effector ID | Locus tag (Gene) | Classification | Cognate immunity protein | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|---|
| EFF00433 | NT01EI_RS11900 | - | - | Edwardsiella ictaluri 93-146 | chromosome (NC_012779) | 2633808..2634299 (+) | 238920627 |
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Experimental investigation has been performed. Bioinformatics investigation has been performed.
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Immunity protein ID | Locus tag (Gene) | Cognate effector | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID |
|---|---|---|---|---|---|---|
| No matching records found | ||||||
Experimental investigation has been performed.
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Accessory protein ID | Locus tag (Gene) | Type | Organism | Replicon (Accession) | Coordinates (Strand) | NCBI ID | Related structure protein | Related effector |
|---|---|---|---|---|---|---|---|---|
| No matching records found | ||||||||