Detailed information of regulator
Summary
| Regulator ID | REG0205  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | TCS regulatory pathway |
| KEGG pathway (determined by BlastKOALA) | Biofilm formation - Pseudomonas aeruginosa (map02025) |
| Related T6SS | T6SS00346 (Type i4b) |
| Strain | Edwardsiella ictaluri 93-146 |
| Replicon | chromosome |
| Sequence | Protein sequence (231 a.a.); Nucleotide sequence (693 bp) |
| Description | the T6SS translocon protein, EvpC, was secreted by ΔesrA::km but not by ΔesrB::km or ΔesrC. |
| Reference |
External database links
| Locus tag (Gene) | NT01EI_RS04200 (EsrC) |
| Coordinates (Strand) | 933326..934018 (-) |
| NCBI ID | 737638726 |
| RefSeq | NC_012779 |
| Uniprot ID | Q1ACA1_EDWIC |
| KEGG ID | - |
| KEGG pathway (determined by BlastKOALA) | map02025 |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| T6SS translocon protein EvpC secretion | ↓ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| HTH_18 | PF12833.9 | 2.7e-24 | 144..222 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-230 | MPNLHLLLVTGPDNIASLPEPGVLLIADSRPPGIASTRHTRLFSYPCNLLHGICRDLQHLMYSGPDPISPPQPLPITMAPGLLKTLLRLADADDETMLRLVLAYSLTLECQRTSTLLRSLLTADADLFDTLYRHRLEPWPVARYADLFGLSQRKFNQLFNEKFGMAPKRWLLRQRLGHARQLLETTSKKVIDVALESGFCNAAHFSDCFRRHFSQSPSEVRRASHHHRAA |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9607 | - | - |
Protein sequence of regulator: 231 a.a. .
>REG0205 NC_012779:c934018-933326 [Edwardsiella ictaluri 93-146]
MPNLHLLLVTGPDNIASLPEPGVLLIADSRPPGIASTRHTRLFSYPCNLLHGICRDLQHLMYSGPDPISPPQPLPITMAP
GLLKTLLRLADADDETMLRLVLAYSLTLECQRTSTLLRSLLTADADLFDTLYRHRLEPWPVARYADLFGLSQRKFNQLFN
EKFGMAPKRWLLRQRLGHARQLLETTSKKVIDVALESGFCNAAHFSDCFRRHFSQSPSEVRRASHHHRAA*
MPNLHLLLVTGPDNIASLPEPGVLLIADSRPPGIASTRHTRLFSYPCNLLHGICRDLQHLMYSGPDPISPPQPLPITMAP
GLLKTLLRLADADDETMLRLVLAYSLTLECQRTSTLLRSLLTADADLFDTLYRHRLEPWPVARYADLFGLSQRKFNQLFN
EKFGMAPKRWLLRQRLGHARQLLETTSKKVIDVALESGFCNAAHFSDCFRRHFSQSPSEVRRASHHHRAA*
Nucleotide sequence of regulator: 693 bp .
>REG0205 NC_012779:c934018-933326 [Edwardsiella ictaluri 93-146]
ATGCCCAATTTGCATCTACTGCTCGTCACCGGTCCAGATAACATCGCGTCTCTTCCTGAGCCCGGCGTACTGCTGATCGC
TGACTCACGACCGCCAGGCATCGCGTCGACCCGGCATACCAGGCTATTTAGCTATCCATGCAATCTTCTGCACGGCATAT
GCCGTGATTTACAGCACCTGATGTACAGTGGTCCGGACCCTATATCTCCCCCTCAACCGTTGCCCATCACCATGGCGCCG
GGCCTGCTGAAAACACTGCTGCGGCTGGCGGATGCCGACGATGAAACCATGCTCAGGCTGGTATTGGCCTACAGCCTGAC
CCTGGAGTGTCAGCGGACATCCACTCTGCTGCGATCGCTGTTAACTGCCGATGCCGACCTGTTCGACACGCTCTATCGCC
ATCGGCTCGAACCCTGGCCGGTGGCGCGCTATGCCGATCTCTTCGGTCTGTCACAGCGTAAATTCAACCAGCTGTTCAAC
GAAAAGTTTGGGATGGCGCCGAAACGCTGGCTGCTGCGCCAGCGTCTGGGACATGCCCGTCAGCTGCTCGAAACCACCTC
CAAAAAGGTGATCGACGTGGCGCTGGAGTCCGGATTCTGTAACGCCGCCCATTTCTCTGACTGTTTTCGGCGCCACTTCA
GTCAGTCGCCAAGCGAAGTGCGCCGGGCCAGTCATCACCACCGCGCCGCCTAA
ATGCCCAATTTGCATCTACTGCTCGTCACCGGTCCAGATAACATCGCGTCTCTTCCTGAGCCCGGCGTACTGCTGATCGC
TGACTCACGACCGCCAGGCATCGCGTCGACCCGGCATACCAGGCTATTTAGCTATCCATGCAATCTTCTGCACGGCATAT
GCCGTGATTTACAGCACCTGATGTACAGTGGTCCGGACCCTATATCTCCCCCTCAACCGTTGCCCATCACCATGGCGCCG
GGCCTGCTGAAAACACTGCTGCGGCTGGCGGATGCCGACGATGAAACCATGCTCAGGCTGGTATTGGCCTACAGCCTGAC
CCTGGAGTGTCAGCGGACATCCACTCTGCTGCGATCGCTGTTAACTGCCGATGCCGACCTGTTCGACACGCTCTATCGCC
ATCGGCTCGAACCCTGGCCGGTGGCGCGCTATGCCGATCTCTTCGGTCTGTCACAGCGTAAATTCAACCAGCTGTTCAAC
GAAAAGTTTGGGATGGCGCCGAAACGCTGGCTGCTGCGCCAGCGTCTGGGACATGCCCGTCAGCTGCTCGAAACCACCTC
CAAAAAGGTGATCGACGTGGCGCTGGAGTCCGGATTCTGTAACGCCGCCCATTTCTCTGACTGTTTTCGGCGCCACTTCA
GTCAGTCGCCAAGCGAAGTGCGCCGGGCCAGTCATCACCACCGCGCCGCCTAA