Detailed information of regulator


Summary

Regulator ID REG0204 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS-RR
KEGG pathway (determined by BlastKOALA) Two-component system (map02020)
Related T6SS T6SS00346 experimental (Type i4b)
Strain Edwardsiella ictaluri 93-146
Replicon chromosome
Sequence Protein sequence (215 a.a.); Nucleotide sequence (645 bp)
Description the T6SS translocon protein, EvpC, was secreted by ΔesrA::km but not by ΔesrB::km or ΔesrC.
Reference

External database links

Locus tag (Gene) NT01EI_RS04325 (EsrB)
Coordinates (Strand) 955101..955745 (-)
NCBI ID 506350644
RefSeq NC_012779
Uniprot ID C5BBE4_EDWI9, Q1AC76_EDWIC
KEGG ID eic:NT01EI_0965
KEGG pathway (determined by BlastKOALA) map02020
PDB ID -

  Target
Target Regulation (↓/↑) Target sequence
T6SS translocon protein EvpC secretion -

Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
Response_reg PF00072.26 7.9e-27 10..121
GerE PF00196.21 2.7e-18 151..205

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-214 MTISILPLSILIVEDHALLADGIRNLLDSQPRYRVVGAVSNGLAVYEACQRLSPDLVLLDLGLPGMDGVDVIRQLRRRWNDMRIVVVTASSEARRGSDALAAGALAYVLKQSPQQTLLAAMQHASLGKTFVDPALRLDSLEASSDIAQEPPLTLRERQILKLVAEGNRNRDIAELLSISLKTVETHRLNLMRKLDAHNAAELSNWARRLGVLEV



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9035 - -



  Protein sequence of regulator: 215 a.a.    .

>REG0204 NC_012779:c955745-955101 [Edwardsiella ictaluri 93-146]
MTISILPLSILIVEDHALLADGIRNLLDSQPRYRVVGAVSNGLAVYEACQRLSPDLVLLDLGLPGMDGVDVIRQLRRRWN
DMRIVVVTASSEARRGSDALAAGALAYVLKQSPQQTLLAAMQHASLGKTFVDPALRLDSLEASSDIAQEPPLTLRERQIL
KLVAEGNRNRDIAELLSISLKTVETHRLNLMRKLDAHNAAELSNWARRLGVLEV*

  Nucleotide sequence of regulator: 645 bp    .

>REG0204 NC_012779:c955745-955101 [Edwardsiella ictaluri 93-146]
ATGACTATCTCTATTTTGCCGCTGAGCATTCTGATCGTTGAAGACCATGCCTTGCTGGCCGATGGCATCCGTAATCTCCT
GGACAGTCAGCCCCGCTACCGGGTCGTGGGCGCCGTATCGAATGGACTGGCCGTTTATGAGGCCTGCCAGCGCCTCTCGC
CCGATCTGGTCTTGCTCGATCTGGGTCTGCCGGGCATGGACGGCGTTGATGTAATCCGTCAGCTGCGGCGCCGCTGGAAC
GATATGCGTATCGTCGTCGTCACCGCCTCGTCTGAGGCGCGGCGCGGCAGCGACGCCCTCGCCGCCGGCGCGCTCGCCTA
TGTTCTGAAGCAAAGCCCACAGCAAACCCTGCTGGCAGCAATGCAGCATGCATCACTGGGAAAAACCTTTGTCGATCCCG
CCCTCAGGCTGGACTCCCTGGAGGCCTCTTCCGATATAGCTCAGGAACCGCCCCTGACCCTGCGCGAACGGCAAATACTC
AAGCTGGTCGCCGAGGGTAATCGCAACCGGGATATCGCTGAGCTGCTGTCCATCAGCCTGAAAACCGTGGAGACCCATCG
GCTCAACCTGATGCGCAAGCTGGATGCCCACAACGCGGCGGAGCTGAGCAATTGGGCCCGCCGACTGGGTGTGCTGGAGG
TTTAA