Detailed information of regulator
Summary
| Regulator ID | REG0232  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | TCS regulatory pathway |
| KEGG pathway (determined by BlastKOALA) | - |
| Related T6SS | T6SS00372 (Type i4b) |
| Strain | Edwardsiella tarda EIB202 |
| Replicon | chromosome |
| Sequence | Protein sequence (171 a.a.); Nucleotide sequence (513 bp) |
| Description | Putative activators of esrB as identified by Tn-seq. |
| Reference |
External database links
| Locus tag (Gene) | ETAE_0772 (tadA) |
| Coordinates (Strand) | 850367..850879 (+) |
| NCBI ID | 505698653 |
| RefSeq | NC_013508 |
| Uniprot ID | A0A0H3DS36_EDWTF |
| KEGG ID | etd:ETAF_0715 |
| KEGG pathway (determined by BlastKOALA) | - |
| PDB ID | - |
Target
| Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| ETAE_0886 (esrB) promoter | ↓ | - |
Pfam domain hit(s) of regulator
| Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| MafB19-deam | PF14437.8 | 1.1e-32 | 5..151 |
Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
| Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-170 | VTQRDDSDWMRHALQLAEKARAQGEVPVGAVLVLNDRVIGEGWNRPITRHDPTAHAEIMALQQGGAIMQNYRLLEATLYVTLEPCVMCAGAMVHSRIRRLVYGAPDLKTGAAGSLLDVLGHPGMNHRIEVCGGVLADACAAQLSDFFRQRRAQKRAERDARRRAERDDAE |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
| Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9770 | - | - |
Protein sequence of regulator: 171 a.a. .
>REG0232 NC_013508:850367-850879 [Edwardsiella tarda EIB202]
VTQRDDSDWMRHALQLAEKARAQGEVPVGAVLVLNDRVIGEGWNRPITRHDPTAHAEIMALQQGGAIMQNYRLLEATLYV
TLEPCVMCAGAMVHSRIRRLVYGAPDLKTGAAGSLLDVLGHPGMNHRIEVCGGVLADACAAQLSDFFRQRRAQKRAERDA
RRRAERDDAE*
VTQRDDSDWMRHALQLAEKARAQGEVPVGAVLVLNDRVIGEGWNRPITRHDPTAHAEIMALQQGGAIMQNYRLLEATLYV
TLEPCVMCAGAMVHSRIRRLVYGAPDLKTGAAGSLLDVLGHPGMNHRIEVCGGVLADACAAQLSDFFRQRRAQKRAERDA
RRRAERDDAE*
Nucleotide sequence of regulator: 513 bp .
>REG0232 NC_013508:850367-850879 [Edwardsiella tarda EIB202]
GTGACGCAACGCGATGACAGTGACTGGATGCGCCATGCCCTGCAGCTGGCGGAAAAGGCCCGAGCGCAGGGCGAGGTGCC
GGTCGGCGCCGTTTTGGTATTGAACGATCGGGTGATTGGCGAGGGGTGGAACCGGCCGATAACCCGCCACGATCCGACCG
CGCATGCCGAGATCATGGCGCTGCAGCAGGGCGGGGCCATCATGCAGAATTATCGTCTGCTGGAGGCGACGCTGTACGTG
ACGCTGGAGCCCTGTGTGATGTGCGCCGGGGCGATGGTGCACAGCCGCATTCGGCGGCTGGTGTACGGTGCGCCGGATCT
CAAGACCGGCGCGGCGGGGTCGCTGCTGGATGTCCTGGGGCACCCGGGGATGAATCACCGGATCGAGGTGTGCGGCGGCG
TGTTGGCCGACGCGTGCGCGGCGCAGCTGAGCGATTTCTTTCGCCAGCGGCGGGCGCAGAAGAGGGCCGAGCGCGATGCC
CGGCGCCGCGCCGAGCGCGACGACGCAGAATAG
GTGACGCAACGCGATGACAGTGACTGGATGCGCCATGCCCTGCAGCTGGCGGAAAAGGCCCGAGCGCAGGGCGAGGTGCC
GGTCGGCGCCGTTTTGGTATTGAACGATCGGGTGATTGGCGAGGGGTGGAACCGGCCGATAACCCGCCACGATCCGACCG
CGCATGCCGAGATCATGGCGCTGCAGCAGGGCGGGGCCATCATGCAGAATTATCGTCTGCTGGAGGCGACGCTGTACGTG
ACGCTGGAGCCCTGTGTGATGTGCGCCGGGGCGATGGTGCACAGCCGCATTCGGCGGCTGGTGTACGGTGCGCCGGATCT
CAAGACCGGCGCGGCGGGGTCGCTGCTGGATGTCCTGGGGCACCCGGGGATGAATCACCGGATCGAGGTGTGCGGCGGCG
TGTTGGCCGACGCGTGCGCGGCGCAGCTGAGCGATTTCTTTCGCCAGCGGCGGGCGCAGAAGAGGGCCGAGCGCGATGCC
CGGCGCCGCGCCGAGCGCGACGACGCAGAATAG