Detailed information of regulator


Summary

Regulator ID REG0209 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) Metabolic pathways (map01100); Biosynthesis of secondary metabolites (map01110); Glycerophospholipid metabolism (map00564); Phosphatidylinositol signaling system (map04070)
Related T6SS T6SS00372 experimental (Type i4b)
Strain Edwardsiella tarda EIB202
Replicon chromosome
Sequence Protein sequence (286 a.a.); Nucleotide sequence (858 bp)
Description Putative repressors of esrB as identified by Tn-seq.
Reference
External database links

Locus tag (Gene) ETAE_0743 (cdsA)
Coordinates (Strand) 820052..820909 (+)
NCBI ID 502610607
RefSeq NC_013508
Uniprot ID D0ZCV7_EDWTE, A0A0H3DS04_EDWTF
KEGG ID etd:ETAF_0685, etr:ETAE_0743
KEGG pathway (determined by BlastKOALA) map01100; map01110; map00564; map04070
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
ETAE_0886 (esrB) promoter ↑ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
CTP_transf_1 PF01148.22 4.3e-68 3..279
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Inside 1-6 MLKSRI
Transmembrane helix 7-41 ITALILVPVVIAALFLLPPLGFSLVTLAVCMLAAW
Outside 42-55 EWGQLAGFASRNQR
Transmembrane helix 56-77 IWGAVICGLVLAAMLLGMPEFT
Inside 78-83 RSVHLP
Transmembrane helix 84-106 LIAGSLWTAAGWWIVALALVFFY
Outside 107-120 PRSAGWWRHSRALK
Transmembrane helix 121-143 VLFGIVTILPFFWGMVALRQYGY
Inside 144-149 EANHYR
Transmembrane helix 150-172 GAWWLLYVMFLVWGADSGAYIFG
Outside 173-191 KLFGKNKLAPKVSPGKTWE
Transmembrane helix 192-210 GLIGGLMTSALISWLFGRY
Inside 211-216 APLDVD
Transmembrane helix 217-234 VRVLLVCSVIAALASVLG
Outside 235-265 DLTESMFKREAGIKDSSHLIPGHGGVLDRID
Transmembrane helix 266-283 SLTAAVPVFACLMLLVFG
Inside 284-285 QA


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9907 - -


  Protein sequence of regulator: 286 a.a.    .

>REG0209 NC_013508:820052-820909 [Edwardsiella tarda EIB202]
MLKSRIITALILVPVVIAALFLLPPLGFSLVTLAVCMLAAWEWGQLAGFASRNQRIWGAVICGLVLAAMLLGMPEFTRSV
HLPLIAGSLWTAAGWWIVALALVFFYPRSAGWWRHSRALKVLFGIVTILPFFWGMVALRQYGYEANHYRGAWWLLYVMFL
VWGADSGAYIFGKLFGKNKLAPKVSPGKTWEGLIGGLMTSALISWLFGRYAPLDVDVRVLLVCSVIAALASVLGDLTESM
FKREAGIKDSSHLIPGHGGVLDRIDSLTAAVPVFACLMLLVFGQA*

  Nucleotide sequence of regulator: 858 bp    .

>REG0209 NC_013508:820052-820909 [Edwardsiella tarda EIB202]
TTGCTGAAGTCGCGCATTATTACTGCATTAATTTTGGTCCCGGTGGTGATTGCCGCCCTGTTCTTGCTGCCGCCGCTGGG
ATTCTCGCTGGTGACGCTCGCCGTCTGTATGCTGGCCGCCTGGGAGTGGGGGCAGCTGGCCGGTTTCGCCAGTCGCAATC
AGCGTATCTGGGGCGCCGTGATCTGTGGCCTGGTGCTGGCCGCCATGCTGCTGGGGATGCCCGAGTTCACCCGCAGCGTT
CATCTACCGCTGATCGCCGGTTCGCTGTGGACCGCCGCCGGCTGGTGGATTGTGGCGCTGGCGCTGGTGTTCTTTTACCC
GCGCTCAGCTGGCTGGTGGCGTCACTCGCGCGCGCTGAAGGTGCTGTTTGGCATCGTCACCATTCTGCCCTTCTTCTGGG
GGATGGTGGCGCTGCGTCAGTATGGCTATGAGGCCAATCATTATCGCGGTGCCTGGTGGCTGCTGTATGTCATGTTCCTG
GTATGGGGGGCCGACTCGGGCGCCTATATCTTTGGCAAGCTGTTCGGTAAGAACAAGCTGGCGCCGAAGGTGTCACCGGG
GAAAACCTGGGAGGGGCTTATCGGCGGACTGATGACCTCTGCGCTGATCTCGTGGCTGTTTGGGCGCTATGCGCCGCTGG
ATGTCGATGTTCGCGTGCTGTTAGTCTGCTCGGTTATCGCCGCGCTGGCCTCTGTGCTGGGCGATCTGACGGAGAGCATG
TTCAAGCGCGAGGCGGGCATTAAGGACAGTAGTCACCTGATCCCCGGCCACGGCGGCGTACTGGATCGCATCGATAGCCT
GACGGCGGCGGTGCCGGTATTTGCCTGCCTGATGCTGTTGGTTTTTGGCCAGGCCTAA