Detailed information of regulator


Summary

Regulator ID REG0224 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) Metabolic pathways (map01100); Biosynthesis of amino acids (map01230); Cysteine and methionine metabolism (map00270)
Related T6SS T6SS00372 experimental (Type i4b)
Strain Edwardsiella tarda EIB202
Replicon chromosome
Sequence Protein sequence (233 a.a.); Nucleotide sequence (699 bp)
Description Putative repressors of esrB as identified by Tn-seq.
Reference

External database links

Locus tag (Gene) ETAE_2773 (mtnN)
Coordinates (Strand) 2910743..2911441 (+)
NCBI ID 502612632
RefSeq NC_013508
Uniprot ID D0ZD44_EDWTE, A0A0H3DXE1_EDWTF
KEGG ID etd:ETAF_2513, etr:ETAE_2773
KEGG pathway (determined by BlastKOALA) map01100; map01230; map00270
PDB ID -

  Target
Target Regulation (↓/↑) Target sequence
ETAE_0886 (esrB) promoter -

Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
PNP_UDP_1 PF01048.22 2.2e-47 2..226

Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-232 MKVGIIGAMEQEVTLLRDRIENRQTLSLAGCEIYTGRLHGVEVALLKSGIGKVSAAMGTTLLLDHCRPDVVINTGSAGGLASTLRVGDIVISDEVRYHDADVTAFGYQPGQMAGCPAAFSADAALIALAERCISALQLNAVRGLICSGDAFINGAEPLARIRRTFPQVAAVEMEAAAIGHVCHAFQTPFVVVRAISDVADQESHISFDEFLKVAAEQSTLMVEAMLRALAAQ



Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.8760 - -



  Protein sequence of regulator: 233 a.a.    .

>REG0224 NC_013508:2910743-2911441 [Edwardsiella tarda EIB202]
MKVGIIGAMEQEVTLLRDRIENRQTLSLAGCEIYTGRLHGVEVALLKSGIGKVSAAMGTTLLLDHCRPDVVINTGSAGGL
ASTLRVGDIVISDEVRYHDADVTAFGYQPGQMAGCPAAFSADAALIALAERCISALQLNAVRGLICSGDAFINGAEPLAR
IRRTFPQVAAVEMEAAAIGHVCHAFQTPFVVVRAISDVADQESHISFDEFLKVAAEQSTLMVEAMLRALAAQ*

  Nucleotide sequence of regulator: 699 bp    .

>REG0224 NC_013508:2910743-2911441 [Edwardsiella tarda EIB202]
ATGAAAGTAGGCATCATTGGCGCCATGGAGCAGGAAGTTACCCTGCTGCGCGACCGCATCGAAAATCGTCAGACCCTCAG
CCTGGCCGGCTGTGAAATCTATACTGGCCGCCTGCACGGCGTTGAGGTTGCGCTGCTGAAGTCCGGCATCGGCAAAGTCT
CTGCGGCGATGGGAACCACCCTGCTGCTGGATCACTGCCGCCCGGACGTGGTGATCAATACCGGCTCCGCCGGCGGCCTG
GCCAGCACCCTGCGGGTCGGTGACATCGTTATCTCCGACGAGGTGCGCTACCACGACGCCGACGTCACCGCCTTTGGCTA
TCAGCCGGGACAGATGGCCGGTTGTCCGGCGGCCTTTAGCGCCGACGCGGCGCTGATCGCCCTGGCCGAACGCTGCATCT
CTGCGCTGCAGCTGAACGCCGTGCGCGGCCTGATCTGCAGCGGCGACGCCTTCATCAACGGCGCCGAGCCGTTGGCTCGC
ATTCGCCGTACCTTCCCGCAGGTCGCCGCGGTAGAGATGGAGGCGGCGGCTATCGGCCACGTTTGCCACGCCTTCCAGAC
CCCGTTCGTGGTGGTGCGCGCCATCTCCGACGTCGCCGATCAGGAATCTCACATCAGCTTTGATGAGTTCCTCAAGGTCG
CCGCCGAGCAGTCCACCTTGATGGTGGAAGCGATGCTGCGCGCCCTGGCTGCCCAGTAA