Detailed information of regulator
Summary
| Regulator ID | REG0207  |
| Regulator type | protein |
| Regulatory pathway (from literatures) | TCS regulatory pathway |
| KEGG pathway (determined by BlastKOALA) | - |
| Related T6SS | T6SS00372 (Type i4b) |
| Strain | Edwardsiella tarda EIB202 |
| Replicon | chromosome |
| Sequence | Protein sequence (376 a.a.); Nucleotide sequence (1128 bp) |
| Description | Putative repressors of esrB as identified by Tn-seq. |
| Reference |
External database links
| Locus tag (Gene) | ETAE_0035 |
| Coordinates (Strand) | 35881..37008 (+) |
| NCBI ID | 502609898 |
| RefSeq | NC_013508 |
| Uniprot ID | UPI0001BD047C |
| KEGG ID | - |
| KEGG pathway (determined by BlastKOALA) | - |
| PDB ID | - |
Target
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Target | Regulation (↓/↑) | Target sequence |
|---|---|---|
| ETAE_0886 (esrB) promoter | ↑ | - |
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Pfam domain hit(s) of regulator
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Domain | Pfam ID | E-value | Aligned region |
|---|---|---|---|
| Peptidase_M78 | PF06114.15 | 1.4e-11 | 175..280 |
| HTH_3 | PF01381.24 | 2.1e-07 | 10..64 |
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Transmembrane helices
- Transmembrane helices are predicted using TMHMM 2.0 software.
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Prediction | Region | Sequence |
|---|---|---|
| Outside | 1-375 | MAIEFYGERLRLARLLKGYTLQELGDAVFVTRQSIHQYESDVRAPANDVRNALAEFLQVSTDFFGVPLSGDVKPEQCHFRKRQTTPAGVKERVQAYSTILEQLVAELHEHLDMPENGFNLIDNSKIVELTPPLIEKIAEGARIRWGLTPDAPIDNMVNVVENQGAIVTCFDGVSEKVDALSVNRKFPIIIRNTAKESACRMRFDLAHECGHLIMHDGIETGCKQTEREADAFASAFLFPRKSFAREFPSCLGIGGMIDWKKVYALKTRWKVSAKAIIYRAHFLGFINAQQYRSANVWFSQTRQTKKEKLDDQIPLEEPHVLEESLAILKEHLGISFDMLAEKIKVRPELLADISGIKYIPAIDDGYDEIVVPFKF |
Signal peptides
- Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
- Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
- Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
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Prediction | Probability | Cleavage site | Signal peptide sequence |
|---|---|---|---|
| Other | 0.9945 | - | - |
Protein sequence of regulator: 376 a.a. .
>REG0207 NC_013508:35881-37008 [Edwardsiella tarda EIB202]
MAIEFYGERLRLARLLKGYTLQELGDAVFVTRQSIHQYESDVRAPANDVRNALAEFLQVSTDFFGVPLSGDVKPEQCHFR
KRQTTPAGVKERVQAYSTILEQLVAELHEHLDMPENGFNLIDNSKIVELTPPLIEKIAEGARIRWGLTPDAPIDNMVNVV
ENQGAIVTCFDGVSEKVDALSVNRKFPIIIRNTAKESACRMRFDLAHECGHLIMHDGIETGCKQTEREADAFASAFLFPR
KSFAREFPSCLGIGGMIDWKKVYALKTRWKVSAKAIIYRAHFLGFINAQQYRSANVWFSQTRQTKKEKLDDQIPLEEPHV
LEESLAILKEHLGISFDMLAEKIKVRPELLADISGIKYIPAIDDGYDEIVVPFKF*
MAIEFYGERLRLARLLKGYTLQELGDAVFVTRQSIHQYESDVRAPANDVRNALAEFLQVSTDFFGVPLSGDVKPEQCHFR
KRQTTPAGVKERVQAYSTILEQLVAELHEHLDMPENGFNLIDNSKIVELTPPLIEKIAEGARIRWGLTPDAPIDNMVNVV
ENQGAIVTCFDGVSEKVDALSVNRKFPIIIRNTAKESACRMRFDLAHECGHLIMHDGIETGCKQTEREADAFASAFLFPR
KSFAREFPSCLGIGGMIDWKKVYALKTRWKVSAKAIIYRAHFLGFINAQQYRSANVWFSQTRQTKKEKLDDQIPLEEPHV
LEESLAILKEHLGISFDMLAEKIKVRPELLADISGIKYIPAIDDGYDEIVVPFKF*
Nucleotide sequence of regulator: 1128 bp .
>REG0207 NC_013508:35881-37008 [Edwardsiella tarda EIB202]
ATGGCTATAGAATTTTATGGCGAGCGGCTTCGGCTCGCCCGTTTGTTAAAAGGGTACACACTACAAGAGCTGGGTGATGC
AGTTTTTGTTACCCGGCAAAGTATACACCAGTATGAAAGTGACGTTCGGGCACCCGCTAATGATGTACGTAATGCACTGG
CTGAGTTTCTTCAGGTATCCACTGACTTTTTTGGGGTTCCTCTTTCTGGTGACGTCAAGCCAGAGCAATGCCATTTTCGT
AAGAGACAAACAACACCTGCTGGTGTTAAAGAGCGGGTTCAGGCATACAGTACTATTCTTGAGCAGCTCGTTGCTGAGTT
GCATGAACACCTAGATATGCCCGAGAACGGTTTTAATTTGATTGATAATAGTAAGATTGTAGAATTAACACCGCCATTGA
TAGAAAAGATTGCTGAGGGAGCCCGTATTCGTTGGGGGTTAACACCTGATGCCCCTATAGATAATATGGTCAATGTTGTT
GAAAATCAGGGAGCAATTGTTACCTGTTTTGATGGCGTGTCTGAAAAAGTTGATGCTTTATCTGTTAATAGAAAATTTCC
TATAATAATTCGCAATACTGCGAAGGAAAGTGCATGTCGAATGCGTTTTGATTTGGCCCATGAATGTGGTCATTTAATAA
TGCATGATGGTATTGAGACTGGGTGTAAACAGACAGAGAGAGAGGCTGACGCCTTTGCTAGTGCTTTCTTATTTCCTCGC
AAGTCTTTTGCCAGAGAATTTCCGTCTTGCTTAGGTATTGGCGGAATGATTGACTGGAAGAAAGTGTATGCTTTAAAAAC
TCGATGGAAAGTTAGTGCTAAAGCAATTATTTATAGAGCACATTTCCTGGGTTTTATTAACGCTCAGCAATATAGAAGTG
CTAATGTCTGGTTCAGCCAAACAAGACAAACAAAAAAAGAAAAACTGGACGATCAAATTCCTTTAGAGGAACCTCATGTT
CTTGAGGAAAGTTTGGCAATTTTGAAAGAGCATCTGGGTATATCTTTCGATATGTTAGCTGAAAAGATTAAGGTTAGACC
TGAATTATTAGCAGATATATCAGGCATCAAATACATACCTGCTATTGATGATGGTTATGACGAAATTGTTGTTCCTTTTA
AATTTTGA
ATGGCTATAGAATTTTATGGCGAGCGGCTTCGGCTCGCCCGTTTGTTAAAAGGGTACACACTACAAGAGCTGGGTGATGC
AGTTTTTGTTACCCGGCAAAGTATACACCAGTATGAAAGTGACGTTCGGGCACCCGCTAATGATGTACGTAATGCACTGG
CTGAGTTTCTTCAGGTATCCACTGACTTTTTTGGGGTTCCTCTTTCTGGTGACGTCAAGCCAGAGCAATGCCATTTTCGT
AAGAGACAAACAACACCTGCTGGTGTTAAAGAGCGGGTTCAGGCATACAGTACTATTCTTGAGCAGCTCGTTGCTGAGTT
GCATGAACACCTAGATATGCCCGAGAACGGTTTTAATTTGATTGATAATAGTAAGATTGTAGAATTAACACCGCCATTGA
TAGAAAAGATTGCTGAGGGAGCCCGTATTCGTTGGGGGTTAACACCTGATGCCCCTATAGATAATATGGTCAATGTTGTT
GAAAATCAGGGAGCAATTGTTACCTGTTTTGATGGCGTGTCTGAAAAAGTTGATGCTTTATCTGTTAATAGAAAATTTCC
TATAATAATTCGCAATACTGCGAAGGAAAGTGCATGTCGAATGCGTTTTGATTTGGCCCATGAATGTGGTCATTTAATAA
TGCATGATGGTATTGAGACTGGGTGTAAACAGACAGAGAGAGAGGCTGACGCCTTTGCTAGTGCTTTCTTATTTCCTCGC
AAGTCTTTTGCCAGAGAATTTCCGTCTTGCTTAGGTATTGGCGGAATGATTGACTGGAAGAAAGTGTATGCTTTAAAAAC
TCGATGGAAAGTTAGTGCTAAAGCAATTATTTATAGAGCACATTTCCTGGGTTTTATTAACGCTCAGCAATATAGAAGTG
CTAATGTCTGGTTCAGCCAAACAAGACAAACAAAAAAAGAAAAACTGGACGATCAAATTCCTTTAGAGGAACCTCATGTT
CTTGAGGAAAGTTTGGCAATTTTGAAAGAGCATCTGGGTATATCTTTCGATATGTTAGCTGAAAAGATTAAGGTTAGACC
TGAATTATTAGCAGATATATCAGGCATCAAATACATACCTGCTATTGATGATGGTTATGACGAAATTGTTGTTCCTTTTA
AATTTTGA