Detailed information of regulator


Summary

Regulator ID REG0236 experimental
Regulator type protein
Regulatory pathway (from literatures) TCS regulatory pathway
KEGG pathway (determined by BlastKOALA) Two-component system (map02020); Cationic antimicrobial peptide (CAMP) resistance (map01503)
Related T6SS T6SS00372 experimental (Type i4b)
Strain Edwardsiella tarda EIB202
Replicon chromosome
Sequence Protein sequence (233 a.a.); Nucleotide sequence (699 bp)
Description Putative activators of esrB as identified by Tn-seq.
Reference
External database links

Locus tag (Gene) ETAE_3453 (cpxR)
Coordinates (Strand) 3641204..3641902 (+)
NCBI ID 502613290
RefSeq NC_013508
Uniprot ID A0A034SX34_9GAMM, D0ZGW3_EDWTE, A0A076LJJ5_9GAMM, A0A0H3DVD5_EDWTF
KEGG ID ete:ETEE_1672, etd:ETAF_3115, etr:ETAE_3453
KEGG pathway (determined by BlastKOALA) map02020; map01503
PDB ID -
  Target
Target Regulation (↓/↑) Target sequence
ETAE_0886 (esrB) promoter ↓ -
Pfam domain hit(s) of regulator

Domain Pfam ID E-value Aligned region
Response_reg PF00072.26 2.7e-29 4..112
Trans_reg_C PF00486.30 8.6e-22 152..228
Transmembrane helices

  • Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction                 Region     Sequence
Outside 1-232 MNKILLVDDDRELTSLLQELLDLEGFEVIVAHDGEQALAMLDASIDLLLLDVMMPKKNGIDTLKELRQHHQTPVIMLTARGSELDRVLGLELGADDYLPKPFNDRELVARIRAILRRSNWNEQQQNSDSGAPILQVDRLQLNPGRQEASFDGQPLELTGTEFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPERQDGQPWFKTLRGRGYLMVSVS


Signal peptides
  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).
Prediction        Probability Cleavage site Signal peptide sequence
Other 0.9988 - -


  Protein sequence of regulator: 233 a.a.    .

>REG0236 NC_013508:3641204-3641902 [Edwardsiella tarda EIB202]
MNKILLVDDDRELTSLLQELLDLEGFEVIVAHDGEQALAMLDASIDLLLLDVMMPKKNGIDTLKELRQHHQTPVIMLTAR
GSELDRVLGLELGADDYLPKPFNDRELVARIRAILRRSNWNEQQQNSDSGAPILQVDRLQLNPGRQEASFDGQPLELTGT
EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPERQDGQPWFKTLRGRGYLMVSVS*

  Nucleotide sequence of regulator: 699 bp    .

>REG0236 NC_013508:3641204-3641902 [Edwardsiella tarda EIB202]
ATGAATAAGATATTACTGGTTGATGACGATCGCGAACTGACGTCGCTTCTGCAAGAACTTCTTGATCTTGAAGGATTTGA
GGTTATCGTCGCTCACGATGGTGAGCAGGCATTGGCAATGCTGGACGCCAGCATCGATCTGCTGCTGCTGGATGTCATGA
TGCCGAAGAAAAACGGTATCGACACCCTTAAAGAGCTGCGTCAACACCATCAGACGCCGGTCATTATGCTCACCGCCCGC
GGCAGCGAGCTCGACAGGGTGCTGGGGCTGGAGCTGGGGGCAGACGACTACCTGCCGAAACCCTTCAATGATCGCGAGCT
GGTTGCCCGTATCCGGGCTATCCTGCGCCGCTCTAACTGGAATGAGCAGCAGCAAAACAGCGATAGCGGTGCGCCGATCC
TACAGGTCGATCGCCTGCAGCTGAACCCCGGTCGCCAAGAGGCCAGCTTTGACGGCCAGCCCCTGGAGCTCACCGGTACT
GAATTCACGCTGCTGTACCTGCTGGCGCAGCATCTGGGGCAGGTGGTATCGCGCGAACATCTTAGCCAGGAGGTCTTGGG
TAAGCGTCTGACCCCCTTCGATCGCGCTATCGACATGCATATCTCTAACCTCCGCCGCAAACTGCCGGAGCGCCAGGATG
GCCAGCCGTGGTTTAAAACGCTGCGCGGGCGCGGCTATCTGATGGTATCCGTTTCATGA